Fujita Shohei, Hagiwara Akifumi, Kamagata Koji, Aoki Shigeki
From the Department of Radiology, Juntendo University, Tokyo, Japan (S.F., A.H., K.K., S.A.); Department of Radiology, The University of Tokyo, Tokyo, Japan (S.F.); Department of Radiology, The University of Tokyo, Tokyo, Japan (A.H.); Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA (S.F.); and Department of Radiology, Harvard Medical School, Boston, MA (S.F.).
Invest Radiol. 2025 Apr 16. doi: 10.1097/RLI.0000000000001192.
The past decade has witnessed notable advancements in clinical neuroimaging facilitated by technological innovations and significant scientific discoveries. In conjunction with Investigative Radiology's 60th anniversary, this review examines key contributions from the past 10 years, emphasizing the journal's most accessed articles and their impact on clinical practice and research. Advances in imaging technologies, including photon-counting computed tomography, and innovations in low-field and high-field magnetic resonance imaging systems have expanded diagnostic capabilities. Progress in the development and translation of contrast media and rapid quantitative imaging techniques has further improved diagnostic accuracy. Additionally, the integration of advanced data analysis methods, particularly deep learning and medical informatics, has improved image interpretation and operational efficiency. Beyond technological developments, this review highlights basic neuroscience findings, such as the discovery and characterization of the glymphatic system. These insights have provided a deeper understanding of central nervous system physiology and pathology, bridging the gap between research and clinical applications. This review integrates these advancements to provide an overview of the progress and ongoing challenges in clinical neuroimaging, offering insights into its current state and potential future directions within the broader field of radiology.
在技术创新和重大科学发现的推动下，过去十年临床神经影像学取得了显著进展。值《放射学研究》创刊60周年之际，本综述探讨了过去10年的关键贡献，重点介绍了该期刊访问量最高的文章及其对临床实践和研究的影响。成像技术的进步，包括光子计数计算机断层扫描，以及低场和高场磁共振成像系统的创新，扩大了诊断能力。造影剂和快速定量成像技术在研发和转化方面的进展进一步提高了诊断准确性。此外，先进数据分析方法的整合，特别是深度学习和医学信息学，提高了图像解读和操作效率。除了技术发展，本综述还突出了基础神经科学的发现，如类淋巴系统的发现和特征描述。这些见解加深了对中枢神经系统生理学和病理学的理解，弥合了研究与临床应用之间的差距。本综述整合了这些进展，概述了临床神经影像学的进展和持续挑战，深入了解其当前状态以及在更广泛放射学领域的潜在未来方向。
