Liashenko Iu I, Pan'shin A G, Trikhleb V I
Ter Arkh. 1985;57(5):130-3.
Antibodies against antigens of hepatocyte cell membranes are formed in half the patients with hepatitis A and B in one-third of those with pseudotuberculosis. They occur in the period preceding the patients' convalescence rather than in the acute stage of the disease. The recovery of hepatitis patients in whom liver antibodies formed ensued significantly more rapidly than in persons with no autoantibodies. Antibodies against antigens of hepatocyte cell membranes were detectable in different clinical disease patterns. They did not influence the disease progress and witnessed hepatocyte injuries not only in the icteric but also in scarlatiniform and and abdominal disease patterns.
在甲型和乙型肝炎患者中,半数患者以及三分之一的假结核患者会形成针对肝细胞膜抗原的抗体。这些抗体出现在患者康复期之前,而非疾病急性期。形成肝抗体的肝炎患者康复速度明显快于无自身抗体的患者。在不同临床疾病模式中均可检测到针对肝细胞膜抗原的抗体。它们不影响疾病进展,不仅在黄疸型,而且在猩红热样和腹部疾病模式中都表明存在肝细胞损伤。