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[病毒性肝炎中体液型自身免疫反应]

[Autoimmune reactions of the humoral type in viral hepatitis].

作者信息

Liashenko Iu I, Pan'shin A G, Trikhleb V I

出版信息

Ter Arkh. 1985;57(5):130-3.

PMID:4023931
Abstract

Antibodies against antigens of hepatocyte cell membranes are formed in half the patients with hepatitis A and B in one-third of those with pseudotuberculosis. They occur in the period preceding the patients' convalescence rather than in the acute stage of the disease. The recovery of hepatitis patients in whom liver antibodies formed ensued significantly more rapidly than in persons with no autoantibodies. Antibodies against antigens of hepatocyte cell membranes were detectable in different clinical disease patterns. They did not influence the disease progress and witnessed hepatocyte injuries not only in the icteric but also in scarlatiniform and and abdominal disease patterns.

摘要

在甲型和乙型肝炎患者中,半数患者以及三分之一的假结核患者会形成针对肝细胞膜抗原的抗体。这些抗体出现在患者康复期之前,而非疾病急性期。形成肝抗体的肝炎患者康复速度明显快于无自身抗体的患者。在不同临床疾病模式中均可检测到针对肝细胞膜抗原的抗体。它们不影响疾病进展,不仅在黄疸型,而且在猩红热样和腹部疾病模式中都表明存在肝细胞损伤。

相似文献

1
[Autoimmune reactions of the humoral type in viral hepatitis].[病毒性肝炎中体液型自身免疫反应]
Ter Arkh. 1985;57(5):130-3.
2
Antibodies against human liver-specific protein (LSP) in acute and chronic viral hepatitis types A, B and non-A, non-B.甲型、乙型和非甲非乙型急慢性病毒性肝炎患者体内抗人肝脏特异性蛋白(LSP)抗体
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[Autoimmune manifestations in acute viral hepatitides].[急性病毒性肝炎中的自身免疫表现]
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Antibodies to liver cell membrane antigens in chronic active hepatitis (CAH). III. Partial characterization of the liver cell membrane antigens and comparison of reactivities in sera from patients with various liver diseases.慢性活动性肝炎(CAH)中肝细胞膜抗原的抗体。III. 肝细胞膜抗原的部分特性及不同肝病患者血清反应性的比较。
Clin Exp Immunol. 1984 Aug;57(2):429-37.
6
[Immunopathology of chronic liver diseases].[慢性肝病的免疫病理学]
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Autoimmune mechanisms in chronic hepatitis B and delta virus infections.慢性乙型肝炎和丁型病毒感染中的自身免疫机制。
Eur J Gastroenterol Hepatol. 1995 Jul;7(7):615-21.
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Molecular species of hepadnavirus core and envelope polypeptides in hepatocyte plasma membrane of woodchucks with acute and chronic viral hepatitis.
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9
[Liver cell membrane autoantibody (LMA) in chronic liver disease].[慢性肝病中的肝细胞膜自身抗体(LMA)]
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Cellular and humoral immune reactions in chronic active liver disease. II. Lymphocyte subsets and viral antigens in liver biopsies of patients with acute and chronic hepatitis B.慢性活动性肝病中的细胞免疫和体液免疫反应。II. 急慢性乙型肝炎患者肝活检中的淋巴细胞亚群和病毒抗原
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