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[脂质过氧化作用在心肌梗死愈合评估中的应用]

[Lipid peroxidation in the evaluation of healing of myocardial infarction].

作者信息

Malaia L T, Reus L P, Bondarenko M I

出版信息

Ter Arkh. 1985;57(5):52-8.

PMID:4023943
Abstract

The authors studied the time-course of lipid peroxidation with special reference to malonic dialdehyde in blood serum comparatively to the time-course of uricemia in 189 patients with acute large-focal myocardial infarction. It was established that the time-course of malonic aldehyde and uric acid is characterized by a consistent increase which reaches the maximal values at the height of the destructive phase of myocardial infarction as well as by the differences in uncomplicated and complicated healing. The joint index of destruction was developed, permitting one to compare the concentrations of malonic dialdehyde and uric acid in blood serum and to exercise an efficacious biochemical "tracing" of the healing.

摘要

作者研究了189例急性大面积局灶性心肌梗死患者血清中脂质过氧化的时间进程,特别关注丙二醛,并与尿酸血症的时间进程进行了比较。结果表明,丙二醛和尿酸的时间进程表现为持续升高,在心肌梗死破坏期达到最大值,且在愈合过程中单纯愈合和复杂愈合存在差异。制定了联合破坏指数,可用于比较血清中丙二醛和尿酸的浓度,并对愈合过程进行有效的生化“追踪”。

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