Tkachenko V M
Ter Arkh. 1985;57(5):75-9.
The author examined 22 patients with postinfarction heart aneurysm to evaluate the myocardial reserves of the preserved myocardium with the use of the strophanthine test. The time-course of changes in the central hemodynamics, contractile function and segmental myocardial contractility of the left ventricle was evaluated. It was disclosed that the positive inotropic effect of strophanthine depends on the degree of the atherosclerotic lesions of the coronary arteries supplying blood to the zone of the preserved myocardium. In patients with postinfarction heart aneurysm and multiple demonstrable lesions of the coronary artery, administration of strophanthine brought about the deterioration of myocardial contractility of the left ventricle. No relationship was found between the initial status of the hemodynamics and the inotropic effect of strophanthine.
作者检查了22例心肌梗死后心脏室壁瘤患者，以通过使用毒毛花苷试验评估存活心肌的心肌储备。评估了中心血流动力学、收缩功能和左心室节段性心肌收缩力的时间变化过程。结果发现，毒毛花苷的正性肌力作用取决于为存活心肌区域供血的冠状动脉粥样硬化病变程度。在心肌梗死后心脏室壁瘤且冠状动脉有多处明显病变的患者中，给予毒毛花苷会导致左心室心肌收缩力恶化。未发现血流动力学的初始状态与毒毛花苷的正性肌力作用之间存在关联。
