Soopyl'd Iu Kh, Laane E Ia, Uuskiula M M, Altraia E M
Ter Arkh. 1986;58(5):93-5.
A study was made of a vasodilating effect of nifedipine on the hemodynamics of 30 patients with chronic postinfarction left ventricular aneurysm, with chronic cardiovascular insufficiency of the II-III degree according to NYHA. A mean value of the acontractile segment on ventriculograms was 32.5 +/- 1.7%. The main parameters of systemic hemodynamics were studied by a method of integral body rheography 1 hour before and after sublingual intake of 20 mg of nifedipine (Corinfar, GDR) at rest, after exercise and during rehabilitation. An increase in the stroke and cardiac indices at rest by an average of 16% was revealed including a noticeable nifedipine effect in patients with elevated final diastolic pressure or arterial tension. During physical exercise a tendency toward an increase in the cardiac output was observed, mainly at the expense of a rise of the stroke volume after drug intake.
对30例慢性心肌梗死后左心室室壁瘤患者的血液动力学进行了一项研究，这些患者根据纽约心脏协会（NYHA）分级有II - III级慢性心血管功能不全。心室造影上无收缩节段的平均值为32.5 +/- 1.7%。采用整体人体血流描记法，在静息状态、运动后及康复期间，于舌下含服20毫克硝苯地平（德国东德Corinfar）前后1小时，研究全身血液动力学的主要参数。结果显示，静息时每搏输出量和心脏指数平均增加16%，在终末舒张压或动脉压升高的患者中，硝苯地平的作用尤为显著。在体育锻炼期间，观察到心输出量有增加的趋势，这主要是由于服药后每搏输出量的增加。
