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Two heads are better than one: a synergistic strategy for conquering graft--host disease.

作者信息

Stolz Daiana, Giesler Sophie, Zeiser Robert

机构信息

Clinic of Respiratory Medicine, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg.

Department of Medicine I, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg.

出版信息

Haematologica. 2025 Jul 1;110(7):1466-1468. doi: 10.3324/haematol.2025.287776. Epub 2025 Apr 17.

DOI:10.3324/haematol.2025.287776
PMID:40241575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12208156/
Abstract
摘要

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本文引用的文献

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Lower incidence of chronic graft--host disease after ruxolitinib plus extracorporeal photopheresis versus ruxolitinib alone in steroid-refractory acute graft--host disease following allogeneic stem cell transplantation.在异基因干细胞移植后对类固醇难治性急性移植物抗宿主病的治疗中，与单独使用鲁索替尼相比，鲁索替尼联合体外光分离置换术治疗后慢性移植物抗宿主病的发生率更低。
Haematologica. 2025 Jul 1;110(7):1536-1544. doi: 10.3324/haematol.2024.286824. Epub 2025 Mar 20.
2
Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity.脂联素可减轻免疫检查点抑制剂诱导的炎症，而不阻断抗肿瘤免疫。
Cancer Cell. 2025 Feb 10;43(2):269-291.e19. doi: 10.1016/j.ccell.2025.01.004.
3
Expression of glucocorticoid receptor and HDACs in airway smooth muscle cells is associated with response to steroids in COPD.
糖皮质激素受体和 HDACs 在气道平滑肌细胞中的表达与 COPD 对类固醇的反应相关。
Respir Res. 2024 May 29;25(1):227. doi: 10.1186/s12931-024-02769-3.
4
Ruxolitinib for Glucocorticoid-Refractory Chronic Graft-versus-Host Disease.芦可替尼治疗糖皮质激素难治性慢性移植物抗宿主病。
N Engl J Med. 2021 Jul 15;385(3):228-238. doi: 10.1056/NEJMoa2033122.
5
Ruxolitinib-ECP combination treatment for refractory severe chronic graft-versus-host disease.芦可替尼-ECP 联合治疗难治性重度慢性移植物抗宿主病。
Bone Marrow Transplant. 2021 Apr;56(4):909-916. doi: 10.1038/s41409-020-01122-8. Epub 2020 Nov 17.
6
Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy.急性移植物抗宿主病——生物学过程、预防与治疗
N Engl J Med. 2017 Nov 30;377(22):2167-2179. doi: 10.1056/NEJMra1609337.
7
MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT signaling in dendritic cells after stem cell transplantation.干细胞移植后，微小RNA-146a通过靶向树突状细胞中的JAK/STAT信号通路降低主要组织相容性复合体II类分子的表达。
Leukemia. 2017 Dec;31(12):2732-2741. doi: 10.1038/leu.2017.137. Epub 2017 May 9.
8
Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey.芦可替尼用于异基因干细胞移植后对皮质类固醇难治的移植物抗宿主病：一项多中心调查
Leukemia. 2015 Oct;29(10):2062-8. doi: 10.1038/leu.2015.212. Epub 2015 Jul 31.
9
Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease.治疗性 JAK1/2 阻断在移植物抗宿主病中的活性。
Blood. 2014 Jun 12;123(24):3832-42. doi: 10.1182/blood-2013-12-543736. Epub 2014 Apr 7.