Villa Roberto Edoardo, Azimonti Giovanna, Bonos Eleftherios, Christensen Henrik, Durjava Mojca, Dusemund Birgit, Gehring Ronette, Glandorf Boet, Kouba Maryline, López-Alonso Marta, Marcon Francesca, Nebbia Carlo, Pechová Alena, Prieto-Maradona Miguel, Röhe Ilen, Theodoridou Katerina, de Lourdes Bastos Maria, Brantom Paul, Chesson Andrew, Schlatter Josef, Westendorf Johannes, Dulak-Lis Maria, Manini Paola
EFSA J. 2025 Apr 16;23(4):e9367. doi: 10.2903/j.efsa.2025.9367. eCollection 2025 Apr.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 1-methoxy-4-(prop-1-()-enyl)benzene (-anethole) and eugenol as sensory feed additives for all avian species. The additives are already authorised for use in all animal species except fish and poultry. The additives under assessment, -anethole (from either chemical synthesis or natural origin) and eugenol of natural origin, are considered of no safety concern for species (chickens and turkeys) for fattening and of being very unlikely to induce adverse effects in long-living and reproductive animals (laying hens) up to the maximum proposed use levels of 25 mg/kg complete feed. These conclusions are extrapolated to physiologically-related minor species. No safety concern would be expected for the consumer of animal products from the use of -anethole and eugenol up to the maximum proposed use level in feed. The use of -anethole and eugenol as feed additives is considered safe for the environment. Regarding user safety, -anethole is not irritant to skin and eyes but is a dermal sensitiser. Eugenol is irritant to skin and eyes and is a dermal sensitiser. When handling -anethole or eugenol, exposure of unprotected users to estragole or methyleugenol may occur. Therefore, to reduce the risk, the exposure of the users should be minimised. Since -anethole and eugenol are used in food as flavourings, and their function in feed is essentially the same as that in food, no further demonstration of efficacy is necessary.
应欧盟委员会的要求,欧洲食品安全局(EFSA)被要求就1-甲氧基-4-(丙-1-烯基)苯(茴香脑)和丁香酚作为所有禽类的感官饲料添加剂的安全性和有效性发表科学意见。这些添加剂已被批准用于除鱼类和家禽以外的所有动物物种。所评估的添加剂,即化学合成或天然来源的茴香脑和天然来源的丁香酚,在育肥动物(鸡和火鸡)中使用时,在最高建议使用水平为每千克全价饲料25毫克的情况下,被认为对这些物种没有安全问题,并且极不可能对长寿和繁殖动物(产蛋母鸡)产生不良影响。这些结论可外推至生理相关的小型物种。在饲料中使用茴香脑和丁香酚,直至建议的最高使用水平,预计动物产品消费者不会有安全问题。将茴香脑和丁香酚用作饲料添加剂被认为对环境是安全的。关于使用者安全,茴香脑对皮肤和眼睛无刺激性,但具有皮肤致敏性。丁香酚对皮肤和眼睛有刺激性,且具有皮肤致敏性。在处理茴香脑或丁香酚时,未受保护的使用者可能会接触到草蒿脑或甲基丁香酚。因此,为降低风险,应尽量减少使用者的接触。由于茴香脑和丁香酚在食品中用作调味剂,且它们在饲料中的功能与在食品中的基本相同,因此无需进一步证明其有效性。