Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Brantom Paul, Chesson Andrew, Schlatter Josef, Schrenk Dieter, Westendorf Johannes, Manini Paola, Pizzo Fabiola, Dusemund Birgit
EFSA J. 2023 Mar 9;21(3):e07875. doi: 10.2903/j.efsa.2023.7875. eCollection 2023 Mar.
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the leaves of L. (laurel leaf oil), when used as a sensory additive for all animal species. The additive contains up to 4% methyleugenol. The use of the additive at 2 mg/kg complete feed in dogs and cats was considered of low concern. For other long-living and reproductive animals, the use of the additive at 10 mg/kg was considered of concern. For short-living animals, the Panel had no safety concern when the additive is used at 10 mg/kg complete feed for turkeys for fattening, piglets and other growing Suidae, pigs for fattening, veal calves (milk replacer), cattle for fattening and other growing ruminants, horses and rabbits for meat production, salmonids and other fin fish; and at 8.5 mg/kg for chickens for fattening, other growing poultry and other minor species for fattening. The use of laurel leaf oil up to the highest level in feed which was considered of no concern for target animals was also expected to be of no concern for consumers. The additive should be considered as irritant to skin and eyes and the respiratory tract. Due to the high concentration of methyleugenol (≥ 1%), the additive was classified by the applicant as suspected of causing genetic defects and of causing cancer and should be handled accordingly. The use of the additive under the proposed conditions of use was not expected to pose a risk for the environment. Since the leaves of and their preparations were recognised to flavour food and their function in feed would be the same, no further demonstration of efficacy was considered necessary.
应欧盟委员会的要求,欧洲食品安全局动物饲料添加剂和产品或物质专家小组(FEEDAP)被要求就月桂叶精油用作所有动物种类的感官添加剂时的安全性和有效性提供科学意见。该添加剂含有高达4%的甲基丁香酚。在犬猫全价饲料中以2mg/kg的剂量使用该添加剂被认为风险较低。对于其他长寿和繁殖动物,以10mg/kg的剂量使用该添加剂被认为存在风险。对于寿命较短的动物,当该添加剂在育肥火鸡、仔猪和其他生长猪科动物、育肥猪、犊牛(代乳粉)、育肥牛和其他生长反刍动物、肉用马和兔子、鲑科鱼类及其他有鳍鱼类的全价饲料中以10mg/kg的剂量使用,以及在育肥鸡、其他生长家禽和其他育肥小型动物的全价饲料中以8.5mg/kg的剂量使用时,专家小组认为不存在安全问题。在被认为对目标动物无风险的饲料中使用最高水平的月桂叶精油,预计对消费者也无风险。该添加剂应被视为对皮肤、眼睛和呼吸道有刺激性。由于甲基丁香酚浓度高(≥1%),申请人将该添加剂归类为疑似导致基因缺陷和致癌物质,应相应处理。在拟议的使用条件下使用该添加剂预计不会对环境构成风险。由于月桂叶及其制剂被认可用于食品调味,且其在饲料中的功能相同,因此无需进一步证明其有效性。