Rocha Verônica França, Barbosa Matheus Sales, Neves Euclimeire da Silva, Santos Valmira de Jesus, Rego Renata Ferreira da Silva, Pessoa Tiago Lôbo, Ribeiro Marcelo Telles, Santos Jessica Lais Almeida Dos, Pereira Felicidade Mota, Reis Joice Neves
Secretaria de Saúde do Estado da Bahia, Instituto Couto Maia, Salvador, BA, Brazil.
Fundação Oswaldo Cruz, Instituto Gonçalo Moniz, Salvador, BA, Brazil.
Epidemiol Serv Saude. 2025 Apr 14;34:e20240135. doi: 10.1590/S2237-96222024v34e20240135.en. eCollection 2025.
To address the occurrence of an outbreak of vancomycin-resistant Enterococcus in inpatient units intended for COVID-19 patients in a hospital in Salvador, Brazil, specialized in infectious diseases, which underwent several adaptations with effect from March 2020.
This is a descriptive study of patients with positive culture results for vancomycin-resistant Enterococcus between January 2021 and December 2023. The vanA/vanB genotype was defined by real-time polymerase chain reaction, and the clonal profile, by pulsed-field gel electrophoresis. Descriptive analyses were performed and presented as proportions.
Fifteen Enterococcus spp. infected/colonized patients were identified, of which 7 were E. faecalis, 7 were E. faecium and 1 was E. gallinarum. Two clonal profiles were identified: E. faecalis profile A and E. faecium profile C. The vanA genotype was predominant. Possible cross-contamination of disinfected materials and other dirty materials used for bathing and waste disposal was detected in utility/sluice room sinks.
The vancomycin-resistant Enterococcus outbreak in the inpatient units was controlled after implementing a unidirectional flow of disinfection of materials in utility/sluice rooms.
应对巴西萨尔瓦多一家专门治疗传染病的医院中，2020年3月起进行了多项调整的新冠患者住院病房发生的耐万古霉素肠球菌暴发。
这是一项针对2021年1月至2023年12月期间耐万古霉素肠球菌培养结果呈阳性患者的描述性研究。通过实时聚合酶链反应确定vanA/vanB基因型，通过脉冲场凝胶电泳确定克隆图谱。进行描述性分析并以比例形式呈现。
共识别出15例感染/定植肠球菌的患者，其中7例为粪肠球菌，7例为屎肠球菌，1例为鹑鸡肠球菌。识别出两种克隆图谱：粪肠球菌图谱A和屎肠球菌图谱C。vanA基因型占主导。在杂物间/水闸室水槽中检测到用于沐浴和废物处理的消毒材料与其他脏污材料可能存在交叉污染。
在杂物间/水闸室实施材料单向消毒流程后，住院病房的耐万古霉素肠球菌暴发得到了控制。
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