Almekdash Mhd Hasan, Han Jaehwan, Guffey Danielle, Christie Israel C, Helmer Drew A, Wu Tianshi David
Center for Innovations in Quality, Effectiveness, and Safety, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas; and.
Section of Health Services Research.
Ann Am Thorac Soc. 2025 Aug;22(8):1176-1182. doi: 10.1513/AnnalsATS.202408-835OC.
Service members exposed to burn pit emissions may be at risk for adverse health outcomes. The Department of Veterans Affairs offers screening medical evaluations for these individuals, but the benefit of this strategy is unknown. To determine the effect of a medical evaluation for Veterans participating in the Airborne Hazards and Open Burn Pit Registry (AHOBPR), the national registry program for service members exposed to burn pit emissions. We selected all Veterans who participated in the AHOBPR and requested a medical evaluation from 2016 to 2020. We identified cohorts of Veterans who self-reported symptoms on a registry questionnaire of possible cardiovascular, pulmonary, or sinus disease. Participants who completed the medical evaluation were matched by high-dimensional propensity score to those who instead completed a primary care visit. For each cohort, the primary outcome was the receipt of additional care consistent with that disease category, defined as the occurrence of a symptom-related diagnostic test or establishment of care in an associated specialty clinic. In an exploratory analysis, we also determined whether completing the AHOBPR medical evaluation was associated with a shorter time to diagnosis of new medical conditions. The relationship between completion of the medical evaluation and study outcomes was estimated via Cox proportional hazards regression. We identified 27,192 Veterans who requested a medical evaluation, of whom 63% reported symptoms of possible cardiovascular disease, 25% of pulmonary disease, and 43% of sinus disease. After matching, the medical evaluation was associated with a higher hazard of receiving care for cardiovascular (hazard ratio [HR], 1.37; 95% confidence interval [CI], 1.23-1.51), pulmonary (HR, 1.58; 95% CI, 1.39-1.80), and sinus disease (HR, 1.33; 95% CI, 1.13-1.56). In a symptom-agnostic exploratory analysis, the medical evaluation was associated with a similar time to diagnosis of most medical conditions compared with the primary care visit. Among Veterans with symptoms suggestive of cardiovascular, pulmonary, or sinus disease, the AHOBPR medical evaluation was associated with a shorter time to receipt of symptom-related care compared with a primary care visit. A purpose-built toxic exposure medical evaluation appears to be an effective strategy to improve the identification of conditions that may be related to military exposures.
接触燃烧坑排放物的军人可能面临不良健康后果的风险。退伍军人事务部为这些人提供筛查性医学评估,但该策略的益处尚不清楚。为了确定参与机载危害与露天燃烧坑登记处(AHOBPR)的退伍军人进行医学评估的效果,AHOBPR是一个针对接触燃烧坑排放物的军人的全国登记计划。我们选取了所有在2016年至2020年期间参与AHOBPR并要求进行医学评估的退伍军人。我们确定了在登记问卷上自我报告可能患有心血管、肺部或鼻窦疾病症状的退伍军人队列。完成医学评估的参与者通过高维倾向评分与完成初级保健就诊的参与者进行匹配。对于每个队列,主要结局是接受与该疾病类别相符的额外护理,定义为出现与症状相关的诊断测试或在相关专科诊所建立护理。在一项探索性分析中,我们还确定完成AHOBPR医学评估是否与新疾病诊断时间缩短有关。通过Cox比例风险回归估计医学评估完成情况与研究结局之间的关系。我们确定了27192名要求进行医学评估的退伍军人,其中63%报告有心血管疾病可能症状,25%有肺部疾病症状,43%有鼻窦疾病症状。匹配后,医学评估与因心血管疾病接受护理的更高风险相关(风险比[HR],1.37;95%置信区间[CI],1.23 - 1.51),肺部疾病(HR,1.58;95% CI,1.39 - 1.80),以及鼻窦疾病(HR,1.33;95% CI,1.13 - 1.56)。在一项无症状特异性的探索性分析中,与初级保健就诊相比,医学评估与大多数疾病的诊断时间相似。在有心血管、肺部或鼻窦疾病提示症状的退伍军人中,与初级保健就诊相比,AHOBPR医学评估与接受症状相关护理的时间缩短有关。专门构建的有毒物质暴露医学评估似乎是一种有效的策略,可改善对可能与军事暴露相关疾病的识别。