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少数族裔与可改变的痴呆风险:基于英国证据的范围综述

Minoritised ethnic groups and modifiable dementia risk: a scoping review of UK-based evidence.

作者信息

Jordão Magda, Gong Lin, Andre Deirdre, Akhtar Amirah, Nwofe Emmanuel, Hawkins Rebecca, Best Kate, Parveen Sahdia, Windle Karen, Clegg Andrew

机构信息

Academic Unit for Ageing and Stroke Research, University of Leeds, Leeds, UK

Academic Unit for Ageing and Stroke Research, Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.

出版信息

J Epidemiol Community Health. 2025 Aug 8;79(9):670-677. doi: 10.1136/jech-2024-222654.

Abstract

BACKGROUND

People from minoritised ethnic groups are more likely to be impacted by dementia. In the general population, dementia may be prevented or delayed by up to 40% by reducing risk in 12 modifiable risk factors (MRF). However, minoritised ethnic groups are not systematically included.

OBJECTIVES

We conducted a scoping review following Joanna Briggs Institute guidance to map: (1) which minoritised ethnic groups have been included in UK research on dementia MRF, (2) for which MRF and (3) using which research methods.

ELIGIBILITY CRITERIA

Eligible studies analysed one or more of the 12 MRFs among minoritised ethnic groups.

EVIDENCE SOURCES

Medline, Embase Classic+Embase, PsycInfo, Web of Science, CINAHL and grey literature were searched.

CHARTING METHODS

Patient and public involvement with minoritised ethnic groups and professionals informed the data extraction tool. We use frequencies and graphs in data description.

RESULTS

We screened 7748 records, assessed 122 full text records and included 14 studies, which mostly used broad ethnic groups. Hypertension, diabetes and depression were studied as predictors of dementia in 10, eight and six studies, respectively, compared with low social contact and air pollution in just two each. Measures of MRF lacked consistency, and data per ethnic group were not reported in several studies. Research examining interactions in combinations of MRFs was lacking.

CONCLUSIONS

More research is needed with specific ethnic groups, consistent measures and focusing on discrimination and MRF interaction and severity. This will be key to personalised risk reduction with diverse communities.

摘要

背景

少数族裔人群更易受到痴呆症的影响。在一般人群中,通过降低12个可改变的风险因素(MRF),痴呆症的发病可预防或延缓达40%。然而,少数族裔人群并未被系统纳入相关研究。

目的

我们按照乔安娜·布里格斯研究所的指导方针进行了一项范围综述,以梳理:(1)英国痴呆症MRF研究中纳入了哪些少数族裔群体;(2)针对哪些MRF;(3)采用了哪些研究方法。

纳入标准

符合条件的研究分析了少数族裔群体中的一个或多个12个MRF。

证据来源

检索了Medline、Embase Classic+Embase、PsycInfo、Web of Science、CINAHL和灰色文献。

图表方法

少数族裔群体的患者和公众参与以及专业人员为数据提取工具提供了信息。我们在数据描述中使用频率和图表。

结果

我们筛选了7748条记录,评估了122篇全文记录,纳入了14项研究,这些研究大多使用宽泛的种族群体。分别有10项、8项和6项研究将高血压、糖尿病和抑郁症作为痴呆症的预测因素进行研究,而低社交接触和空气污染的研究各仅有2项。MRF的测量缺乏一致性,多项研究未报告每个种族群体的数据。缺乏对MRF组合相互作用的研究。

结论

需要针对特定种族群体开展更多研究,采用一致的测量方法,并关注歧视、MRF相互作用和严重程度。这对于不同社区进行个性化风险降低至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ad/12418548/e5d36928f15c/jech-79-9-g001.jpg

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