英格兰不同族裔人群中痴呆症的发病率、发病年龄和生存情况：一项基于电子健康记录的纵向研究。
Incidence, age at diagnosis and survival with dementia across ethnic groups in England: A longitudinal study using electronic health records.
机构信息
University College London, London, UK.
London School of Hygiene and Tropical Medicine, London, UK.
出版信息
Alzheimers Dement. 2023 Apr;19(4):1300-1307. doi: 10.1002/alz.12774. Epub 2022 Sep 1.
INTRODUCTION
We investigated the incidence of diagnosed dementia and whether age at diagnosis and survival afterward differs among the United Kingdom's three largest ethnic groups.
METHODS
We used primary care electronic health records, linked Hospital Episode Statistics and mortality data for adults aged ≥65 years. We compared recorded dementia incidence 1997-2018, age at diagnosis, survival time and age at death after diagnosis in White, South Asian, and Black people.
RESULTS
Dementia incidence was higher in Black people (incidence rate ratios [IRR] 1.22, 95% CI 1.15-1.30). South Asian and Black people with dementia had a younger age of death than White participants (mean difference for South Asian participants -2.97 years, (95% CI -3.41 to -2.53); and Black participants -2.66 years, (95% CI -3.08 to -2.24).
DISCUSSION
South Asian and Black peoples' younger age of diagnosis and death means targeted prevention and care strategies for these groups should be prioritized and tailored to facilitate take-up.
引言
我们调查了英国三个最大的种族中确诊痴呆症的发病率，以及诊断后的年龄和存活时间是否存在差异。
方法
我们使用了初级保健电子健康记录，结合了医院事件统计数据和≥65 岁成年人的死亡率数据。我们比较了 1997 年至 2018 年记录的痴呆症发病率、诊断时的年龄、存活时间以及诊断后死亡时的年龄，比较对象为白种人、南亚裔和黑人。
结果
黑人的痴呆症发病率更高（发病率比 [IRR] 1.22，95%CI 1.15-1.30）。南亚裔和黑人痴呆症患者的死亡年龄比白人参与者小（南亚裔参与者的平均差异为-2.97 岁，95%CI-3.41 至-2.53；黑人参与者为-2.66 岁，95%CI-3.08 至-2.24）。
讨论
南亚裔和黑人的诊断和死亡年龄更小，这意味着应优先为这些群体制定有针对性的预防和护理策略，并针对这些群体进行调整以促进其接受。
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