Schmidt R, Pullmann H, Steigleder G K
Z Hautkr. 1985 Jun 15;60(12):947-56.
In vivo exposition of guinea pig epidermal cells to infra-red irradiation (IR) led to significant, biphasic reduction of the proliferating activity after 6 h and 72 h. Not before 168 h after exposure, the proliferating activity rose above the normal rate. The quantitative alterations of DNA-proliferating cells went along with prolongation of the S-phase and the cell cycle. UV-irradiated cells react earlier by reduction of the DNA-proliferating activity directly followed by stages of hyperproliferation.
豚鼠表皮细胞在体内暴露于红外辐射(IR)后,在6小时和72小时时增殖活性出现显著的双相降低。暴露后168小时之前,增殖活性并未超过正常水平。DNA增殖细胞的数量变化与S期和细胞周期的延长同时发生。紫外线照射的细胞反应更早,先是DNA增殖活性降低,随后是过度增殖阶段。