Jiang Jiao, Yang Xiaoge, Du Feifan, Zheng Wei, Wang Jiancang
Department of Ophthalmology, Hebei Children's Hospital, Shijiazhuang, 050000, Hebei, China.
BMC Ophthalmol. 2025 Apr 17;25(1):217. doi: 10.1186/s12886-025-04058-z.
To observe the effectiveness of intense pulsed light(IPL) treatment as an adjuvant treatment of refractory seasonal allergic conjunctivitis in children.
A total of 31 patients with refractory seasonal allergic conjunctivitis who did not respond well to anti-allergic drug treatment were randomly selected to receive drug therapy combined with IPL treatment (17 patients) and drug treatment alone (14 patients) for 1 week, and the ocular surface symptom questionnaire and ocular surface sign score were performed before and after treatment, respectively.
After treatment, the IPL group had significantly lower scores in eye rubbing, blinking, eye itching, discharge, tearing, and total scores than before treatment (P < 0.05), while there was no significant difference in foreign body sense scores before and after treatment (P > 0.05). There were no significant differences in eye rubbing, blinking, eye itching, discharge, foreign body sensation, tearing, and total score between the control group after treatment (P > 0.05). After treatment, the scores of ocular signs in the IPL group and the control group were lower than those before treatment, and the difference was statistically significant (P < 0.01).
IPL therapy is effective in improving ocular surface symptoms in children with refractory seasonal allergic conjunctivitis, especially in suppressing eye itching, with good results.
观察强脉冲光（IPL）治疗作为儿童难治性季节性过敏性结膜炎辅助治疗的效果。
随机选取31例对抗过敏药物治疗反应不佳的难治性季节性过敏性结膜炎患者，分别接受药物联合IPL治疗（17例）和单纯药物治疗（14例），为期1周，分别在治疗前后进行眼表症状问卷和眼表体征评分。
治疗后，IPL组在揉眼、眨眼、眼痒、分泌物、流泪及总分方面的得分均显著低于治疗前（P＜0.05），而治疗前后异物感得分差异无统计学意义（P＞0.05）。治疗后对照组在揉眼、眨眼、眼痒、分泌物、异物感、流泪及总分方面与IPL组比较，差异均无统计学意义（P＞0.05）。治疗后，IPL组和对照组的眼表体征评分均低于治疗前，差异有统计学意义（P＜0.01）。
IPL治疗可有效改善儿童难治性季节性过敏性结膜炎的眼表症状，尤其在抑制眼痒方面效果良好。
