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全球、区域和国家胸骨骨折及/或一根或多根肋骨骨折的负担:对发病率及到2030年的伤残损失生命年的系统分析

Global, regional, and national burden of fracture of sternum and/or fracture of one or more ribs: a systematic analysis of incidence, YLDs with projections to 2030.

作者信息

Wang Zhizhi, Cai Yikuan, Tong Yu, Li Huajie, Zhou Hu, Ou Tongyin, Ye Tianlan, Zhang Jiangsheng, Cai Kaican, Chen Zhiming

机构信息

Department of Thoracic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

出版信息

Front Public Health. 2025 Apr 3;13:1565478. doi: 10.3389/fpubh.2025.1565478. eCollection 2025.

Abstract

BACKGROUND

Sternal and/or rib fractures represent a growing global health challenge. Despite their significant clinical and public health implications, epidemiological studies on these injuries remain limited. Utilizing the Global Burden of Disease 2019 (GBD2019) database, this study evaluates the worldwide burden of sternal and/or rib fractures and projects trends through 2030 to inform policy development.

METHODS

We analyzed global incidence, age-standardized incidence rate (ASIR), years lived with disability (YLDs), age-standardized YLD rate (ASYR) and estimated annual percentage change (EAPC) of sternal and/or rib fractures across geographic regions, nations, age-sex groups, and socio-demographic index (SDI) quintiles using GBD2019 data. The Bayesian age-period-cohort (BAPC) model was employed to forecast trends until 2030.

RESULTS

In 2019, global incident cases of sternal/rib fractures reached 4.1 million (44% increase since 1990), with YLDs at 190,000 (62% rise since 1990). While ASIR and ASYR showed modest declines, the absolute burden remained substantial. East Asia and high-income North America both exhibited the highest incident cases and YLDs. Central Latin America and Western Saharan Africa demonstrated the steepest incidence growth, whereas the Caribbean experienced the most pronounced YLD increases. Nationally, China reported the highest absolute burden, while Greenland had the highest ASIR and ASYR. Males carried over 60% of the burden. Also, there was a negative correlation between EAPC and national SDI. Projections indicate that the global burden of disease will continue to rise by 2030.

CONCLUSION

The escalating burden of sternal/rib fractures demands targeted interventions. Prioritizing injury prevention in high-burden regions (e.g., East Asia), addressing male-dominated occupational/behavioral risks, and optimizing infrastructure such as medical transport in low-SDI settings are critical policy priorities. Sustained surveillance through standardized reporting systems is essential for monitoring progress.

摘要

背景

胸骨和/或肋骨骨折是一个日益严峻的全球健康挑战。尽管这些损伤具有重大的临床和公共卫生影响,但关于此类损伤的流行病学研究仍然有限。本研究利用《2019年全球疾病负担》(GBD2019)数据库,评估全球胸骨和/或肋骨骨折的负担,并预测到2030年的趋势,以为政策制定提供信息。

方法

我们使用GBD2019数据,分析了胸骨和/或肋骨骨折在地理区域、国家、年龄性别组以及社会人口指数(SDI)五分位数中的全球发病率、年龄标准化发病率(ASIR)、伤残调整生命年(YLDs)、年龄标准化YLD率(ASYR)以及估计年百分比变化(EAPC)。采用贝叶斯年龄-时期-队列(BAPC)模型预测到2030年的趋势。

结果

2019年,全球胸骨/肋骨骨折的发病病例达到410万例(自1990年以来增加了44%),YLDs为19万例(自1990年以来上升了62%)。虽然ASIR和ASYR略有下降,但绝对负担仍然很大。东亚和高收入北美地区的发病病例和YLDs均最高。中拉丁美洲和西撒哈拉非洲的发病率增长最为陡峭,而加勒比地区的YLDs增加最为显著。在国家层面,中国报告的绝对负担最高,而格陵兰的ASIR和ASYR最高。男性承担了超过60%的负担。此外,EAPC与国家SDI之间存在负相关。预测表明,到2030年全球疾病负担将继续上升。

结论

胸骨/肋骨骨折负担的不断升级需要有针对性的干预措施。在高负担地区(如东亚)优先预防损伤、解决以男性为主的职业/行为风险以及在低SDI环境中优化医疗运输等基础设施是关键的政策重点。通过标准化报告系统进行持续监测对于监测进展至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/066b/12003264/23b1eba532d7/fpubh-13-1565478-g001.jpg

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