Suppr超能文献

一名老年患者的累及脊柱和肋骨的多骨型纤维发育不良。

Polyostotic fibrous dysplasia in an elderly patient involving spine and ribs.

作者信息

Çağan Pinar, Safaei Seyedehtina, Kimiaei Ali, Kutlu Cemal Asim

机构信息

Thoracic Surgery, Bahçeşehir University, Istanbul, Türkiye.

出版信息

Indian J Thorac Cardiovasc Surg. 2025 May;41(5):569-573. doi: 10.1007/s12055-024-01842-2. Epub 2024 Oct 25.

Abstract

Fibrous dysplasia (FD) is a benign skeletal disorder characterized by the replacement of normal bone with fibro-osseous tissue, which often causes bone expansion and deformities. Polyostotic fibrous dysplasia (PFD), involving multiple bones, is uncommon and rarely affects the spine and ribs, with fewer than 40 reported cases in the literature. We present the case of a 65-year-old male who presented with sudden left-sided back pain and left sided ptosis. Imaging revealed extensive FD affecting the cervicothoracic vertebrae and the adjacent ribs. Surgical resection involving thoracotomy and excision of the pathological ribs and spinal lesions was performed. The procedure ensured the preservation of vital structures and achieved complete tumor removal. Surgical resection remains crucial in managing symptomatic PFD of the spine and ribs with the aim of complete tumor removal. Long-term follow-up is essential to monitor recurrence and evaluate patient outcomes.

摘要

骨纤维异常增殖症(FD)是一种良性骨骼疾病,其特征是正常骨被纤维骨组织替代,常导致骨质膨胀和畸形。多骨型骨纤维异常增殖症(PFD)累及多块骨骼,较为罕见,很少影响脊柱和肋骨,文献报道病例少于40例。我们报告一例65岁男性患者,表现为突发左侧背痛和左侧上睑下垂。影像学检查显示广泛的骨纤维异常增殖症累及颈胸椎及相邻肋骨。实施了包括开胸手术以及切除病变肋骨和脊柱病变的手术切除。该手术确保了重要结构的保留并实现了肿瘤的完全切除。手术切除对于治疗有症状的脊柱和肋骨PFD以实现肿瘤完全切除仍然至关重要。长期随访对于监测复发和评估患者预后至关重要。

相似文献

1
Polyostotic fibrous dysplasia in an elderly patient involving spine and ribs.
Indian J Thorac Cardiovasc Surg. 2025 May;41(5):569-573. doi: 10.1007/s12055-024-01842-2. Epub 2024 Oct 25.
2
Fibrous Dysplasia Involving Cranio-Facial Region Treated with Zolendronic Acid: A Single Institutional Experience and Review of Literature.
Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4270-4279. doi: 10.1007/s12070-024-04835-0. Epub 2024 Jun 29.
3
Pain in fibrous dysplasia: identifying nociceptive mechanisms in a preclinical model.
J Bone Miner Res. 2025 Jun 25;40(7):891-903. doi: 10.1093/jbmr/zjaf039.
4
A Case of McCune Albright Syndrome With Rare Extensive Polyostotic Fibrous Dysplasia.
Clin Nucl Med. 2025 Jul 1;50(7):e433-e434. doi: 10.1097/RLU.0000000000005674. Epub 2025 Feb 3.
5
Polyostotic fibrous dysplasia: Unveiling the complexity of a rare bone disorder through a case report.
Radiol Case Rep. 2025 May 17;20(8):3846-3850. doi: 10.1016/j.radcr.2025.04.040. eCollection 2025 Aug.
7
Are Current Survival Prediction Tools Useful When Treating Subsequent Skeletal-related Events From Bone Metastases?
Clin Orthop Relat Res. 2024 Sep 1;482(9):1710-1721. doi: 10.1097/CORR.0000000000003030. Epub 2024 Mar 22.
8
Efficacy of antiresorptive agents in fibrous dysplasia and McCune Albright syndrome, a systematic review and meta-analysis.
Rev Endocr Metab Disord. 2023 Dec;24(6):1103-1119. doi: 10.1007/s11154-023-09832-2. Epub 2023 Aug 26.
9
[Malignant transformation of polyostotic fibrous dysplasia in long bone: a clinicopathological analysis of four cases].
Zhonghua Bing Li Xue Za Zhi. 2025 Jun 8;54(6):593-598. doi: 10.3760/cma.j.cn112151-20250122-00055.

本文引用的文献

1
Polyostotic cystic fibrous dysplasia of the spine and ribs.
BMJ Case Rep. 2024 Apr 29;17(4):e260222. doi: 10.1136/bcr-2024-260222.
4
Fibrous dysplasia causing safeguarding concerns.
Arch Dis Child. 2013 Dec;98(12):1003. doi: 10.1136/archdischild-2013-304490. Epub 2013 Aug 21.
5
Fibrous dysplasia.
Arch Pathol Lab Med. 2013 Jan;137(1):134-8. doi: 10.5858/arpa.2012.0013-RS.
6
Bone diseases of the jaws.
Int J Dent. 2010;2010:702314. doi: 10.1155/2010/702314. Epub 2010 Mar 31.
8
Fibrous dysplasia. Pathophysiology, evaluation, and treatment.
J Bone Joint Surg Am. 2005 Aug;87(8):1848-64. doi: 10.2106/JBJS.D.02942.
10
Monostotic fibrous dysplasia of the clivus: MRI and CT findings.
Neuroradiology. 2002 Oct;44(10):847-50. doi: 10.1007/s00234-002-0833-8. Epub 2002 Sep 18.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验