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多骨型纤维发育不良:通过一例病例报告揭示一种罕见骨病的复杂性

Polyostotic fibrous dysplasia: Unveiling the complexity of a rare bone disorder through a case report.

作者信息

Nasri Siham, Benramdane Hicham, Kamaoui Imane, Skiker Imane

机构信息

Faculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.

Department of Radiology, Mohammed VI University Hospital Mohammed I University Oujda, Morocco.

出版信息

Radiol Case Rep. 2025 May 17;20(8):3846-3850. doi: 10.1016/j.radcr.2025.04.040. eCollection 2025 Aug.

Abstract

Polyostotic fibrous dysplasia is a benign but potentially debilitating bone disorder characterized by the gradual replacement of normal bone with fibrous tissue. The polyostotic form, less common than the monostotic form, affects multiple bones, often asymmetrically. Clinical manifestations are variable and may include bone pain, deformities, pathologic fractures. Imaging plays a crucial role in diagnosis. Treatment is primarily symptomatic. We report the case of a 7-year-old girl admitted to our department for intermittent bone pain. History revealed a spontaneous pathological fracture of the left femoral neck. Further investigation with a CT scan revealed polyostotic fibrous dysplasia.

摘要

多骨型纤维发育不良是一种良性但可能导致身体衰弱的骨疾病,其特征是正常骨组织逐渐被纤维组织替代。多骨型比单骨型少见,会累及多块骨骼,且常常不对称。临床表现多样,可能包括骨痛、畸形、病理性骨折。影像学检查在诊断中起关键作用。治疗主要是对症治疗。我们报告一例7岁女孩因间歇性骨痛入住我科的病例。病史显示左侧股骨颈自发性病理性骨折。进一步的CT扫描检查发现为多骨型纤维发育不良。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d32/12145516/a9091f282d6e/gr1.jpg

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