错牙合对儿童和青少年疼痛相关颞下颌关节紊乱症患病率的影响：一项系统评价。

The impact of malocclusion on the prevalence of pain-related temporomandibular disorders in children and adolescents: a systematic review.

作者信息

Szyszka-Sommerfeld Liliana, Sycińska-Dziarnowska Magdalena, Gerreth Karolina, Spagnuolo Gianrico, Woźniak Krzysztof, Czajka-Jakubowska Agata

机构信息

Laboratory for Propaedeutics of Orthodontics and Facial Congenital Defects, Chair of Maxillofacial Orthopaedics and Orthodontics, Pomeranian Medical University in Szczecin, Szczecin, Poland.

Department of Maxillofacial Orthopaedics and Orthodontics, Chair of Maxillofacial Orthopaedics and Orthodontics, Pomeranian Medical University in Szczecin, Szczecin, Poland.

出版信息

Front Neurol. 2025 Apr 3;16:1550110. doi: 10.3389/fneur.2025.1550110. eCollection 2025.

DOI:10.3389/fneur.2025.1550110

PMID:40248012

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12004977/

Abstract

BACKGROUND

The connection between occlusion and temporomandibular disorders (TMD) remains a topic of discussion, and current research does not provide a definitive answer. Pain-related TMD are the most common types of TMD. They include myalgia, arthralgia, and headaches attributed to TMD. This systematic review aims to synthesize the current scientific evidence regarding impact of malocclusion on the prevalence of pain-related TMD in individuals under 18 years.

METHODS

The study was based on a searching of the PubMed, Scopus, Embase, and Web of Science databases. Selection was limited to studies that explored the link between malocclusion and pain-related TMD in young individuals. The Newcastle-Ottawa Scale (NOS) was used to evaluate the quality of the selected research. The certainty of evidence was assessed using the Grading Recommendations Assessment, Development and Evaluation (GRADE) approach. A visual representation of the screening and inclusion processes was created using a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) diagram. The information from the research was then summarized in a descriptive format.

RESULTS

Out of 868 potentially relevant articles initially identified, 13 studies were selected based on the inclusion criteria. The majority of these studies were determined to be of moderate quality, according to the NOS assessment. The certainty of evidence was assessed as low, according to the GRADE approach. Most of the studies showed that malocclusion may be associated with TMD-pain signs/symptoms in children and adolescents. The most frequent relationship was found between the prevalence of pain-related TMD and posterior crossbite, Class II malocclusion, Class III malocclusion, and anterior open bite.

CONCLUSION

Certain types of malocclusion may have an impact on the prevalence of some TMD-pain signs and symptoms in young individuals. However, given the limited reliability of existing research and the inconsistencies observed across studies, additional well-structured, long-term investigations are necessary.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/prospero/, identifier CRD42024570950.

摘要

背景

咬合与颞下颌关节紊乱病（TMD）之间的关系仍是一个讨论的话题，目前的研究并未给出明确答案。疼痛相关的TMD是最常见的TMD类型。它们包括肌痛、关节痛以及归因于TMD的头痛。本系统评价旨在综合当前关于错牙合对18岁以下个体中疼痛相关TMD患病率影响的科学证据。

方法

该研究基于对PubMed、Scopus、Embase和科学网数据库的检索。选择仅限于探索年轻个体中错牙合与疼痛相关TMD之间联系的研究。采用纽卡斯尔-渥太华量表（NOS）评估所选研究的质量。使用推荐分级评估、制定和评价（GRADE）方法评估证据的确定性。使用系统评价和Meta分析的首选报告项目（PRISMA）图对筛选和纳入过程进行可视化展示。然后以描述性格式总结研究信息。

结果

在最初识别出的868篇潜在相关文章中，根据纳入标准选择了13项研究。根据NOS评估，这些研究中的大多数被判定为中等质量。根据GRADE方法，证据的确定性被评估为低。大多数研究表明，错牙合可能与儿童和青少年的TMD疼痛体征/症状相关。在疼痛相关TMD的患病率与后牙反牙合、安氏II类错牙合、安氏III类错牙合和前牙开牙合之间发现了最常见的关系。