[Activity of polymorphic N-acetyltransferase in epilepsy].
作者信息
Barannikov A S, Trubnikov V I
出版信息
Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(6):857-61.
PMID:4024808
Abstract
Activity of polymorphic N-acetyl transferase characterized by bimodality (fast and slow acetylators) in normal subjects was studied in 150 epileptic patients. The epileptic versus normal subjects had a significant predominance of slow acetylators. The data obtained suggest that slow acetylation is one of the possible factors predisposing to epilepsy and responsible for a more severe course of the disease. The results of the study suggest that determination of the activity of polymorphic N-acetyl transferase may serve as a prognostic criterion of epilepsy.
摘要
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