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肺纤维化合并肺癌:2004年至2024年的文献计量分析——研究现状、趋势及未来方向

Pulmonary fibrosis complicated by lung cancer: bibliometric analysis from 2004 to 2024 - research status, trends and future directions.

作者信息

Li Boyang, Wu Fan, Ma Xinlai, Yuan Weishan, Li Jiaqing, Zhang Wei, Liu Xue

机构信息

The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China.

Institute of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.

出版信息

Front Immunol. 2025 Apr 3;16:1514831. doi: 10.3389/fimmu.2025.1514831. eCollection 2025.

Abstract

OBJECTIVE

Although research on the association between pulmonary fibrosis and lung cancer is of great significance, to date, no bibliometric analysis has been conducted on the comorbidity of these two diseases. This study aims to explore the current status and cutting - edge trends in this field through bibliometric analysis, and to establish new directions for future research.

METHODS

Using the Web of Science Core Collection database, statistical calculations, graphic, and data visualization tools such as CiteSpace, VOSviewer, and Biblimatrix - biblioshiny were adopted.

RESULTS

A total of 2,234 original Articles and Reviews on pulmonary fibrosis complicated by lung cancer published between 2004 and 2024 were identified. A slow growth trend in publications related to pulmonary fibrosis complicated by lung cancer was observed. The United States, Japan, and China were the countries with the greatest contributions. Professor Michael Kreuter from Marienhaus Clinic, Mainz, Germany, and the University of Michigan published the most articles. Through cluster analysis of co - cited literature, five main clusters were identified. Keyword analysis predicted that "nintedanib", "pirfenidone", "immunotherapy", etc. might become hot topics in the field of the comorbidity of pulmonary fibrosis and lung cancer.

CONCLUSION

This bibliometric analysis shows that the literature related to the comorbidity of pulmonary fibrosis and lung cancer is on a continuous upward trend. The research hotspots and trends identified in this study provide a reference for in - depth research in this field, aiming to promote the development of research on the comorbidity of pulmonary fibrosis and lung cancer.

摘要

目的

尽管关于肺纤维化与肺癌之间关联的研究具有重要意义,但迄今为止,尚未对这两种疾病的合并症进行文献计量分析。本研究旨在通过文献计量分析探索该领域的现状和前沿趋势,并为未来研究确立新方向。

方法

使用科学网核心合集数据库,采用CiteSpace、VOSviewer和Biblimatrix - biblioshiny等统计计算、图形和数据可视化工具。

结果

共识别出2004年至2024年间发表的2234篇关于肺纤维化合并肺癌的原创文章和综述。观察到肺纤维化合并肺癌相关出版物呈缓慢增长趋势。美国、日本和中国是贡献最大的国家。德国美因茨玛丽恩豪斯诊所和密歇根大学的迈克尔·克罗伊特教授发表的文章最多。通过对共被引文献的聚类分析,确定了五个主要聚类。关键词分析预测“尼达尼布”“吡非尼酮”“免疫疗法”等可能成为肺纤维化和肺癌合并症领域的热点话题。

结论

这项文献计量分析表明,与肺纤维化和肺癌合并症相关的文献呈持续上升趋势。本研究确定的研究热点和趋势为该领域的深入研究提供了参考,旨在促进肺纤维化和肺癌合并症研究的发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d24c/12003117/80fa6b33278c/fimmu-16-1514831-g001.jpg

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