Dengerink H, Miller J, Axelsson A, Vertes D, Van Dalfsen P
Acta Otolaryngol. 1985 Jul-Aug;100(1-2):19-25. doi: 10.3109/00016488509108582.
Histological measures of cochlear vasculature and blood flow were examined in 20 guinea pigs. Sixteen were exposed to octave band noise at 120 dB SPL for 30 min and then permitted to survive after the exposure for 6 h, 18 h, 48 h, or 4 weeks (N = 4 in each group). Control animals were exposed to the laboratory and apparatus but not to the noise and then sacrificed after 48 h (N = 2) or 4 weeks (N = 2). Statistically significant results indicate that the noise exposure resulted in reduced RBCs in the cochlea for animals permitted to survive 6 to 18 h after the noise exposure. These changes, however, were no longer apparent in animals which were permitted to survive 48 h or 4 weeks after the noise exposure. The vascular sequelae of 30 min exposure to 120 dB octave band noise appear to recover within a few days of the exposure.
对20只豚鼠的耳蜗血管系统和血流进行了组织学测量。16只豚鼠暴露于120 dB SPL的倍频程带噪声中30分钟，然后在暴露后存活6小时、18小时、48小时或4周（每组n = 4）。对照动物暴露于实验室和仪器，但不暴露于噪声，然后在48小时（n = 2）或4周（n = 2）后处死。统计学上的显著结果表明，对于在噪声暴露后存活6至18小时的动物，噪声暴露导致耳蜗中的红细胞减少。然而，在噪声暴露后存活48小时或4周的动物中，这些变化不再明显。暴露于120 dB倍频程带噪声30分钟后的血管后遗症似乎在暴露后的几天内恢复。
