玻璃体小带附着于晶状体后赤道部在原发性闭角型青光眼中的作用

The Role of Vitreous Zonule Attachments to the Posterior Lens Equator in Primary Angle Closure Glaucoma.

作者信息

Huang Jie, Li Mubin, Huang Chukai

机构信息

Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong.

Shantou University Medical College, Shantou, Guangdong, China.

出版信息

J Glaucoma. 2025 Jul 1;34(7):528-534. doi: 10.1097/IJG.0000000000002577. Epub 2025 Apr 21.

DOI:10.1097/IJG.0000000000002577

PMID:40249239

Abstract

PRCIS

Shorter axial length was associated with the absence of the attachments between the posterior insertion zone of the vitreous zonules and the posterior lens equator. Primary angle closure disease eyes without vitreous zonules had a more anteriorly rotated ciliary body.

PURPOSE

To assess the clinical significance of the attachments between the posterior insertion zone of the vitreous zonules and the posterior lens equator (PVZ INS-LE strands) and vitreous zonules (VZ) in primary angle closure disease (PACD).

METHODS

This cross-sectional study consisted of 90 PACD and 30 cataract eyes from an eye clinic. PVZ INS-LE strands, VZ, and anterior segment parameters were assessed by ultrasound biomicroscopy (UBM). The presence of PVZ INS-LE strands and VZ was compared between groups. Baseline ocular characteristics and UBM parameters were compared among PACD eyes. Factors associated with the absence of PVZ INS-LE strands and VZ were identified.

RESULTS

Forty percent of control eyes and 71.1% of PACD showed PVZ INS-LE strands absent. PACD 22.2% and no control eyes showed VZ absent. PVZ INS-LE strands absent group had shorter axial length ( P =0.018), larger ciliary-ciliary angle ( P =0.010), and smaller trabecular-ciliary process distance at 750 μm ( P =0.022). Shorter axial length was independently associated with absence of PVZ INS-LE strands (OR=2.230; 95% CI: 1.027-4.838; P =0.043). VZ absent group had larger ciliary-ciliary angle ( P <0.001), smaller trabecular-ciliary angle ( P =0.040), shorter iris-ciliary process distance at 750 μm ( P =0.092), and shorter trabecular-ciliary process distance at 750 μm ( P =0.026).

CONCLUSIONS

PVZ INS-LE strands were less likely to be seen in APACD and their fellow eyes. All types of PACD eyes had less presence of VZ. PACD eyes without VZ appeared to have more anterior rotation of the ciliary body. Shorter AL was independently associated with the absence of PVZ INS-LE strands.

摘要

PRCIS

眼轴较短与玻璃体小带后插入区与晶状体后赤道之间无附着有关。无玻璃体小带的原发性闭角型青光眼患者的睫状体旋转更靠前。

目的

评估玻璃体小带后插入区与晶状体后赤道（PVZ INS-LE束）之间的附着以及玻璃体小带（VZ）在原发性闭角型青光眼（PACD）中的临床意义。

方法

这项横断面研究包括来自眼科诊所的90例PACD患者和30例白内障患者。通过超声生物显微镜（UBM）评估PVZ INS-LE束、VZ和眼前节参数。比较两组之间PVZ INS-LE束和VZ的存在情况。比较PACD患者眼部的基线眼部特征和UBM参数。确定与PVZ INS-LE束和VZ缺失相关的因素。

结果

40%的对照组和71.1%的PACD患者显示PVZ INS-LE束缺失。22.2%的PACD患者和无对照组患者显示VZ缺失。PVZ INS-LE束缺失组眼轴较短（P = 0.018），睫状-睫状角较大（P = 0.010），750μm处小梁-睫状突距离较小（P = 0.022）。较短的眼轴长度与PVZ INS-LE束缺失独立相关（OR = 2.230；95% CI：1.027 - 4.838；P = 0.043）。VZ缺失组睫状-睫状角较大（P < 0.001），小梁-睫状角较小（P = 0.040），750μm处虹膜-睫状突距离较短（P = 0.092），750μm处小梁-睫状突距离较短（P = 0.026）。