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甘油三酯——女性心血管疾病的主要脂质风险因素?

Triglycerides--main lipid risk factor for cardiovascular disease in women?

作者信息

Lapidus L, Bengtsson C, Lindquist O, Sigurdsson J A, Rybo E

出版信息

Acta Med Scand. 1985;217(5):481-9. doi: 10.1111/j.0954-6820.1985.tb03251.x.

DOI:10.1111/j.0954-6820.1985.tb03251.x
PMID:4025004
Abstract

A 12-year longitudinal population study of 1462 women, aged 38-60, was carried out in Gothenburg, Sweden in 1968-69. Women with high initial serum triglyceride values had a higher 12-year incidence of myocardial infarction, stroke and total mortality than the others. The findings for serum triglycerides persisted for myocardial infarction, stroke and total mortality after adjustment for other possible risk factors for ischaemic heart disease such as age, systolic blood pressure, smoking, indices of obesity and serum cholesterol, while serum cholesterol did not predict any end-points studied when taking other risk factors including serum triglycerides into account.

摘要

1968 - 1969年,在瑞典哥德堡对1462名年龄在38 - 60岁之间的女性进行了一项为期12年的纵向人群研究。初始血清甘油三酯值较高的女性,其心肌梗死、中风和全因死亡率的12年发病率高于其他人。在对缺血性心脏病的其他可能危险因素(如年龄、收缩压、吸烟、肥胖指数和血清胆固醇)进行调整后,血清甘油三酯与心肌梗死、中风和全因死亡率之间的关联依然存在,而在考虑包括血清甘油三酯在内的其他危险因素时,血清胆固醇并不能预测所研究的任何终点事件。

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