Nikkilä M, Koivula T, Niemelä K, Sisto T
Department of Clinical Sciences, University of Tampere, Finland.
Br Heart J. 1990 Feb;63(2):78-81. doi: 10.1136/hrt.63.2.78.
Serum triglycerides, high density lipoprotein (HDL) cholesterol, and total cholesterol were measured in 698 patients examined by angiography. The ratio of HDL cholesterol to total cholesterol was significantly lower in patients with single, double, and triple vessel disease than in patients without disease. The serum concentration of triglyceride was significantly higher in patients with single, double, and triple vessel disease than in those without coronary artery disease. Similar proportion of patients with coronary artery disease and without had serum cholesterol concentrations of greater than or equal to 6.5 mmol/l, but total cholesterol was significantly higher in patients with single, double, and triple vessel disease than in those without. HDL cholesterol (less than 1.0 mmol/l), triglycerides (greater than 2.0 mmol/l), and the ratio of HDL cholesterol to total cholesterol (less than 0.20) were significantly better than total cholesterol as indicators of coronary risk.
对698例接受血管造影检查的患者测定了血清甘油三酯、高密度脂蛋白（HDL）胆固醇和总胆固醇。单支血管病变、双支血管病变和三支血管病变患者的HDL胆固醇与总胆固醇之比显著低于无病变患者。单支血管病变、双支血管病变和三支血管病变患者的血清甘油三酯浓度显著高于无冠状动脉疾病的患者。有冠状动脉疾病和无冠状动脉疾病的患者中，血清胆固醇浓度≥6.5 mmol/l的比例相似，但单支血管病变、双支血管病变和三支血管病变患者的总胆固醇显著高于无病变患者。HDL胆固醇（<1.0 mmol/l）、甘油三酯（>2.0 mmol/l）以及HDL胆固醇与总胆固醇之比（<0.20）作为冠状动脉风险指标显著优于总胆固醇。
