重度抑郁症患者的重返工作岗位及功能状况：对支持性就业参与者的纵向研究。
Work re-entry and functioning in people with major depression: a longitudinal study of supported employment participants.
作者信息
Bergdolt Juliane, Hubert Stella, Schreiter Julia, Jenderny Sarah, Beblo Thomas, Driessen Martin, Steinhart Ingmar, Dehn Lorenz B
机构信息
Universitätsklinik für Psychiatrie und Psychotherapie, Evangelisches Klinikum Bethel gGmbH, Universitätsklinikum OWL, Universität Bielefeld, Remterweg 69-71, 33617, Bielefeld, Germany.
Department of Psychology, University of Bielefeld, Universitätsstraße 25, 33615, Bielefeld, Germany.
出版信息
BMC Psychiatry. 2025 Apr 18;25(1):402. doi: 10.1186/s12888-025-06826-z.
BACKGROUND
People with major depression are affected by impaired daily functioning and non-participation in the workforce. At the same time, employment has been associated with improved mental health outcomes. The aim of this study was to examine the relationship between work re-entry and subsequent functioning and depressive symptoms.
METHODS
The present observational study included a sample of 129 participants of a supported employment intervention project in Germany diagnosed with depressive disorders. Participants were assessed before the start of the intervention (baseline) and after two years (follow-up). Functioning and depressive symptom severity were measured using the World Health Organization Disability Assessment Schedule 2 (WHODAS 2.0) and the Beck's Depression Inventory II (BDI-II). After multiple imputation, linear regression analyses were conducted to analyze the relationship between work re-entry and follow-up functioning and symptom severity, controlling for baseline scores and age.
RESULTS
Work re-entry was significantly associated with better overall functioning (p =.002), cognitive functioning (p =.001) and community participation (p =.002), adjusted for baseline scores and age. A significant interaction effect (p =.001) suggested that the association between work re-entry and overall functioning at follow-up was stronger in older participants. After adjustment for baseline functioning and age, work re-entry was not significantly associated with self-care, social interaction and household responsibilities, while associations with mobility (p =.072) and symptom severity (p =.054) were marginally nonsignificant.
CONCLUSIONS
The results support the association between work re-entry and lower disability in people with depression who participated in supported employment. Certain functional domains, especially cognition and participation, may be more closely associated with becoming re-employed. The association between work-re-entry and overall functioning may be stronger in older individuals.
TRIAL REGISTRATION
The data used for this study were collected as part of a clinical trial called "IPS-ZIB" which was prospectively registered with the German register for clinical trials on 12/14/2020 (DRKS; ID: DRKS00023521).
背景
重度抑郁症患者的日常生活功能受损，无法参与劳动力市场。与此同时，就业与心理健康状况的改善相关。本研究的目的是探讨重新就业与后续功能及抑郁症状之间的关系。
方法
本观察性研究纳入了德国一项支持性就业干预项目中的129名被诊断为抑郁症的参与者。在干预开始前（基线）和两年后（随访）对参与者进行评估。使用世界卫生组织残疾评估量表2.0（WHODAS 2.0）和贝克抑郁量表第二版（BDI-II）测量功能和抑郁症状严重程度。经过多次插补后，进行线性回归分析，以分析重新就业与随访时的功能及症状严重程度之间的关系，并对基线分数和年龄进行控制。
结果
在对基线分数和年龄进行调整后，重新就业与更好的整体功能（p = 0.002）、认知功能（p = 0.001）和社区参与（p = 0.002）显著相关。显著的交互作用（p = 0.001）表明，在老年参与者中，重新就业与随访时的整体功能之间的关联更强。在对基线功能和年龄进行调整后，重新就业与自我护理、社交互动和家务责任无显著关联，而与活动能力（p = 0.072）和症状严重程度（p = 0.054）的关联接近显著。
结论
结果支持了参与支持性就业的抑郁症患者重新就业与较低残疾程度之间的关联。某些功能领域，尤其是认知和参与，可能与重新就业的关联更为密切。重新就业与整体功能之间的关联在老年人中可能更强。
试验注册
本研究使用的数据是作为一项名为“IPS-ZIB”的临床试验的一部分收集的，该试验于2020年12月14日在德国临床试验注册中心进行了前瞻性注册（DRKS；ID：DRKS00023521）。
Zotero 插件