Ma Yanjie, Zhang Yifan, Li Rui, Cheng Wenlin, Wu Fang
Wuxi Medical College of Jiangnan University, Jiangnan University, Wuxi, 214122, Jiangsu Province, China.
School of Nursing, Beihua University, Jilin, 132013, Jilin Province, China.
J Neurol. 2025 Apr 19;272(5):350. doi: 10.1007/s00415-025-13085-1.
Parkinson's disease (PD) is the fastest-growing neurodegenerative disorder, affecting over 8.5 million people worldwide, with symptoms that severely impact patients' quality of life. While treatments like levodopa and deep brain stimulation help manage symptoms, they require frequent adjustments and have limitations. Wearable devices offer real-time monitoring of motor and non-motor symptoms, enabling personalized treatment, but challenges related to comfort, usability, and patient adherence hinder their widespread adoption. Many individuals with PD experience discomfort, emotional distress, or interface difficulties, reducing long-term adherence. This study synthesizes qualitative research on patients' experiences with wearables to identify key usability barriers and improve device design for better clinical integration.
Following the Joanna Briggs Institute methodology for qualitative systematic reviews, we searched PubMed, Web of Science, Embase, Cochrane Library, CINAHL, CNKI, WanFang, and VIP databases up to March 3, 2025. Additional gray literature and reference lists were examined manually. Included qualitative studies underwent comprehensive assessment, integration, and analysis.
Nine studies were included, identifying four main themes and eleven sub-themes. The four primary themes were physiological experience, psychological Responses, social Interaction, and Expectation.
This meta-synthesis reveals the dual role of wearable devices in managing Parkinson's disease, improving patient autonomy and disease control while presenting challenges in comfort, reliability, and emotional well-being. The findings emphasize the need for personalized, context-sensitive devices that adapt to fluctuating PD symptoms, address privacy concerns, and seamlessly integrate into clinical practice to improve clinical outcomes and patient adherence.
帕金森病（PD）是增长最快的神经退行性疾病，全球有超过850万人受其影响，其症状严重影响患者的生活质量。虽然左旋多巴和深部脑刺激等治疗方法有助于控制症状，但它们需要频繁调整且有局限性。可穿戴设备可对运动和非运动症状进行实时监测，实现个性化治疗，但与舒适度、可用性和患者依从性相关的挑战阻碍了它们的广泛应用。许多帕金森病患者会感到不适、情绪困扰或存在界面使用困难，从而降低了长期依从性。本研究综合了关于患者使用可穿戴设备体验的定性研究，以确定关键的可用性障碍，并改进设备设计以更好地融入临床。
按照乔安娜·布里格斯研究所定性系统评价方法，我们检索了截至2025年3月3日的PubMed、科学网、Embase、考克兰图书馆、CINAHL、中国知网、万方和维普数据库。另外还手动查阅了灰色文献和参考文献列表。纳入的定性研究进行了全面评估、整合和分析。
纳入了9项研究，确定了4个主要主题和11个子主题。这4个主要主题是生理体验、心理反应、社会互动和期望。
这项元综合研究揭示了可穿戴设备在管理帕金森病中的双重作用，它在提高患者自主性和疾病控制的同时，在舒适度、可靠性和情绪健康方面也带来了挑战。研究结果强调需要有个性化的、因地制宜的设备，以适应帕金森病症状的波动，解决隐私问题，并无缝融入临床实践，以改善临床结果和患者依从性。
