Mitchell R T, Marshall L H, Lefkowitz L B, Stratton C W
Am J Clin Pathol. 1985 Aug;84(2):251-3. doi: 10.1093/ajcp/84.2.251.
The Kodak Ektachem (Eastman Kodak Co., Rochester, NY) is a new clinical chemistry analyzer that uses an enzymatic method to measure creatinine. The authors report the case of a patient with falsely elevated creatinine levels that were caused by the presence of 5-fluorocytosine. A review of the literature confirmed that this can occur, but well documented reports are not found. In order to determine the magnitude of this interference, the authors plotted creatinine levels versus 5-FC concentration. Significant interference is seen with therapeutic levels of 5-FC. Both clinicians and pathologists should be aware of this phenomenon.
柯达Ektachem分析仪（纽约州罗切斯特市伊士曼柯达公司）是一种新型临床化学分析仪，它采用酶法测量肌酐。作者报告了一例患者，其肌酐水平因5-氟胞嘧啶的存在而假性升高。文献回顾证实这种情况可能发生，但未发现充分记录的报告。为了确定这种干扰的程度，作者绘制了肌酐水平与5-氟胞嘧啶浓度的关系图。在5-氟胞嘧啶的治疗浓度下可观察到显著干扰。临床医生和病理学家都应了解这一现象。
