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血液中5-氟胞嘧啶水平的快速测定。

Rapid determination of 5-fluorocytosine levels in blood.

作者信息

Noble M A, Harper B, Grant A G, Bernstein M

出版信息

J Clin Microbiol. 1984 Nov;20(5):996-7. doi: 10.1128/jcm.20.5.996-997.1984.

Abstract

Levels of 5-fluorocytosine in blood were rapidly calculated by determining the amount of competition in the creatinine iminohydrolase (creatinine deiminase; EC 3.5.4.21) assay for creatinine with the Kodak Ektachem system (Eastman Kodak Co., Rochester, N.Y.). The correlation with bioassay values was extremely high (r = 0.982). Standards and samples were highly stable over time.

摘要

通过使用柯达Ektachem系统(纽约州罗切斯特市伊士曼柯达公司)测定肌酐亚氨基水解酶(肌酐脱亚氨酶;EC 3.5.4.21)测定中与肌酐的竞争量,快速计算出血液中5-氟胞嘧啶的水平。与生物测定值的相关性极高(r = 0.982)。标准品和样品随时间推移高度稳定。

相似文献

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Rapid determination of 5-fluorocytosine levels in blood.血液中5-氟胞嘧啶水平的快速测定。
J Clin Microbiol. 1984 Nov;20(5):996-7. doi: 10.1128/jcm.20.5.996-997.1984.
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Rapid fluorimetric determination of 5-fluorocytosine in serum.血清中5-氟胞嘧啶的快速荧光测定法
Clin Chim Acta. 1975 Sep 1;63(2):109-14. doi: 10.1016/0009-8981(75)90152-7.
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Drug Intell Clin Pharm. 1988 Nov;22(11):879-80. doi: 10.1177/106002808802201108.

本文引用的文献

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Strategies in the treatment of systemic fungal infections.系统性真菌感染的治疗策略。
N Engl J Med. 1980 Jan 17;302(3):145-55. doi: 10.1056/NEJM198001173020304.
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Fluorometric measurement of 5-fluorocytosine in biological fluids.
J Pharm Sci. 1973 May;62(5):828-9. doi: 10.1002/jps.2600620531.
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Pharmacological studies with 5-fluorocytosine.5-氟胞嘧啶的药理学研究。
Antimicrob Agents Chemother. 1972 Jun;1(6):476-82. doi: 10.1128/AAC.1.6.476.
5
Creatinine assay by a reaction-kinetic principle.基于反应动力学原理的肌酐测定法。
Clin Chim Acta. 1972 Oct;41:209-17. doi: 10.1016/0009-8981(72)90513-x.
7
Bone marrow toxicity associated with 5-fluorocytosine therapy.与5-氟胞嘧啶治疗相关的骨髓毒性。
Antimicrob Agents Chemother. 1977 Feb;11(2):244-7. doi: 10.1128/AAC.11.2.244.

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