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血液中5-氟胞嘧啶水平的快速测定。

Rapid determination of 5-fluorocytosine levels in blood.

作者信息

Noble M A, Harper B, Grant A G, Bernstein M

出版信息

J Clin Microbiol. 1984 Nov;20(5):996-7. doi: 10.1128/jcm.20.5.996-997.1984.

DOI:10.1128/jcm.20.5.996-997.1984
PMID:6511883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC271494/
Abstract

Levels of 5-fluorocytosine in blood were rapidly calculated by determining the amount of competition in the creatinine iminohydrolase (creatinine deiminase; EC 3.5.4.21) assay for creatinine with the Kodak Ektachem system (Eastman Kodak Co., Rochester, N.Y.). The correlation with bioassay values was extremely high (r = 0.982). Standards and samples were highly stable over time.

摘要

通过使用柯达Ektachem系统(纽约州罗切斯特市伊士曼柯达公司)测定肌酐亚氨基水解酶(肌酐脱亚氨酶;EC 3.5.4.21)测定中与肌酐的竞争量,快速计算出血液中5-氟胞嘧啶的水平。与生物测定值的相关性极高(r = 0.982)。标准品和样品随时间推移高度稳定。

相似文献

1
Rapid determination of 5-fluorocytosine levels in blood.血液中5-氟胞嘧啶水平的快速测定。
J Clin Microbiol. 1984 Nov;20(5):996-7. doi: 10.1128/jcm.20.5.996-997.1984.
2
Falsely elevated serum creatinine levels secondary to the presence of 5-fluorocytosine.由于5-氟胞嘧啶的存在导致血清肌酐水平假性升高。
Am J Clin Pathol. 1985 Aug;84(2):251-3. doi: 10.1093/ajcp/84.2.251.
3
Rapid enzymatic method for measurement of serum flucytosine levels.测定血清氟胞嘧啶水平的快速酶法。
J Antimicrob Chemother. 1986 May;17(5):673-7. doi: 10.1093/jac/17.5.673.
4
False elevation in serum creatinine levels.血清肌酐水平假性升高。
JAMA. 1984 Dec 7;252(21):2962.
5
Gas-chromatographic determination of 5-fluorocytosine in human serum.
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6
An enzymatic method for 5-fluorocytosine.一种测定5-氟胞嘧啶的酶法。
Clin Chem. 1988 Jan;34(1):59-62.
7
[Fluorimetric assay of serum 5-fluorocytosine].[血清5-氟胞嘧啶的荧光测定法]
Pathol Biol (Paris). 1985 Jan;33(1):70-2.
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Rapid fluorimetric determination of 5-fluorocytosine in serum.血清中5-氟胞嘧啶的快速荧光测定法
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Flucytosine interference with serum creatinine determinations.氟胞嘧啶对血清肌酐测定的干扰。
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The Kodak Ektachem 400 Analyzer evaluated for automated enzymic determination of plasma creatinine.对柯达埃克塔化学400分析仪进行了评估,用于血浆肌酐的自动化酶法测定。
Clin Chem. 1983 Jul;29(7):1422-5.

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本文引用的文献

1
High performance liquid chromatographic (HPLC) and other non-biological methods for quantitation of antifungal drugs.
J Antimicrob Chemother. 1982 Dec;10(6):467-78. doi: 10.1093/jac/10.6.467.
2
Strategies in the treatment of systemic fungal infections.系统性真菌感染的治疗策略。
N Engl J Med. 1980 Jan 17;302(3):145-55. doi: 10.1056/NEJM198001173020304.
3
Fluorometric measurement of 5-fluorocytosine in biological fluids.
J Pharm Sci. 1973 May;62(5):828-9. doi: 10.1002/jps.2600620531.
4
Pharmacological studies with 5-fluorocytosine.5-氟胞嘧啶的药理学研究。
Antimicrob Agents Chemother. 1972 Jun;1(6):476-82. doi: 10.1128/AAC.1.6.476.
5
Creatinine assay by a reaction-kinetic principle.基于反应动力学原理的肌酐测定法。
Clin Chim Acta. 1972 Oct;41:209-17. doi: 10.1016/0009-8981(72)90513-x.
6
Rapid, simple bioassay for 5-fluorocytosine in the presence of amphotericin B.在两性霉素B存在的情况下对5-氟胞嘧啶进行快速、简易的生物测定。
Antimicrob Agents Chemother. 1975 Apr;7(4):462-5. doi: 10.1128/AAC.7.4.462.
7
Bone marrow toxicity associated with 5-fluorocytosine therapy.与5-氟胞嘧啶治疗相关的骨髓毒性。
Antimicrob Agents Chemother. 1977 Feb;11(2):244-7. doi: 10.1128/AAC.11.2.244.
8
Evidence for conversion of 5-fluorocytosine to 5-fluorouracil in humans: possible factor in 5-fluorocytosine clinical toxicity.人类体内5-氟胞嘧啶转化为5-氟尿嘧啶的证据:5-氟胞嘧啶临床毒性的可能因素。
Antimicrob Agents Chemother. 1978 Dec;14(6):903-8. doi: 10.1128/AAC.14.6.903.