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超低剂量计算机断层扫描成像在量化骨创伤和疾病中的应用:一项横断面研究

Ultra-Low Dose Computed Tomography Imaging in Quantifying Bone Trauma and Disorders: A Cross-Sectional Study.

作者信息

Zarei Fariba, Ahmadi Seyedeh Marzieh, Dehbani-Zadeh Saber, Jafari Anahita, Akondi Vyas, Chatterjee Sabyasachi, Mirhosseini Seyed Alireza, Ravanfar Haghighi Rezvan

机构信息

Medical Imaging Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran.

Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Iran J Med Sci. 2025 Apr 1;50(4):229-238. doi: 10.30476/ijms.2024.102043.3477. eCollection 2025 Apr.

Abstract

BACKGROUND

X-ray computed tomography (CT) is a standard tool for diagnosing bone abnormalities. CT dose optimization is strongly recommended, due to the stochastic effects of x-ray. This study aims to assess the effectiveness of ultra-low-dose CT (ULD-CT) imaging, reconstructed using an Iterative Reconstruction (IR) algorithm, in detecting bone trauma and disorders.

METHODS

In the present cross-sectional study, 71 patients with CT requests for spine or extremity (limb) bone underwent scanning using standard dose (SD) and ULD-CT protocols, in Shahid Faghihi Hospital, Shiraz, Iran from June 2019 to June 2020. The SD and ULD-CT protocols used 120 kVp and 80 kVp, respectively. The CT images were reconstructed using the standard and IR algorithms. CT dose indices, including the volume CT dose index (CTDI), dose-length product (DLP), and effective dose (ED), were employed. To assess image quality, a five-point scoring system was used. The sensitivity and specificity of the ULD-CT images were calculated.

RESULTS

The findings indicated that ULD-CT images accurately identified 113 out of 118 bone trauma and disorders. The quality of ULD-CT images received "very good", "good" and "acceptable" scores for both spine and extremity (limb) bones. The sensitivity and specificity of ULD-CT images for bone trauma and disorders were 67%-95% and 100%, respectively, with about a 98% dose reduction.

CONCLUSION

The ULD-CT protocol for bone imaging achieved a remarkable dose reduction, while the image quality was reported as acceptable. Consequently, ULD-CT images reconstructed using an IR are suitable and can be tuned further in the future for acceptable use in patients with bone trauma and disorders.

摘要

背景

X射线计算机断层扫描(CT)是诊断骨骼异常的标准工具。由于X射线的随机效应,强烈建议进行CT剂量优化。本研究旨在评估使用迭代重建(IR)算法重建的超低剂量CT(ULD-CT)成像在检测骨创伤和疾病方面的有效性。

方法

在本横断面研究中,2019年6月至2020年6月期间,伊朗设拉子的沙希德·法吉希医院对71例因脊柱或四肢(肢体)骨进行CT检查的患者,分别采用标准剂量(SD)和ULD-CT方案进行扫描。SD和ULD-CT方案分别使用120 kVp和80 kVp。CT图像采用标准算法和IR算法重建。采用了包括容积CT剂量指数(CTDI)、剂量长度乘积(DLP)和有效剂量(ED)在内的CT剂量指标。为评估图像质量,使用了五分制评分系统。计算了ULD-CT图像的敏感性和特异性。

结果

结果表明,ULD-CT图像准确识别出了118例骨创伤和疾病中的113例。ULD-CT图像在脊柱和四肢(肢体)骨方面的质量均获得了“非常好”“好”和“可接受”的评分。ULD-CT图像对骨创伤和疾病的敏感性和特异性分别为67%-95%和100%,剂量降低了约98%。

结论

用于骨成像的ULD-CT方案实现了显著的剂量降低,同时图像质量被报告为可接受。因此,使用IR重建的ULD-CT图像是合适的,并且未来可进一步调整,以便在骨创伤和疾病患者中安全使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0824/12008661/d80208605590/IJMS-50-229-g001.jpg

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