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2
Noninvasive Ventilation for Preoxygenation during Emergency Intubation.紧急插管时预氧合的无创通气。
N Engl J Med. 2024 Jun 20;390(23):2165-2177. doi: 10.1056/NEJMoa2313680. Epub 2024 Jun 13.
3
Interstitial lung disease: a review of classification, etiology, epidemiology, clinical diagnosis, pharmacological and non-pharmacological treatment.间质性肺疾病：分类、病因、流行病学、临床诊断、药物及非药物治疗综述
Front Med (Lausanne). 2024 Apr 18;11:1296890. doi: 10.3389/fmed.2024.1296890. eCollection 2024.
4
Interstitial Lung Disease: A Review.间质性肺疾病：综述。
JAMA. 2024 May 21;331(19):1655-1665. doi: 10.1001/jama.2024.3669.
5
Long-stay ICU patients with frailty: mortality and recovery outcomes at 6 months.长期入住重症监护病房的虚弱患者：6个月时的死亡率和康复结果
Ann Intensive Care. 2024 Feb 24;14(1):31. doi: 10.1186/s13613-024-01261-x.
6
Physiological effects of lung-protective ventilation in patients with lung fibrosis and usual interstitial pneumonia pattern versus primary ARDS: a matched-control study.肺纤维化和普通间质性肺炎模式与原发性 ARDS 患者肺保护性通气的生理效应：一项匹配对照研究。
Crit Care. 2023 Oct 18;27(1):398. doi: 10.1186/s13054-023-04682-5.
7
Recent Advances of Artificial Intelligence Applications in Interstitial Lung Diseases.人工智能在间质性肺疾病中的应用新进展
Diagnostics (Basel). 2023 Jul 6;13(13):2303. doi: 10.3390/diagnostics13132303.
8
Re-hospitalisation predicts poor prognosis after acute exacerbation of interstitial lung disease.再入院预示着间质性肺疾病急性加重后的不良预后。
BMC Pulm Med. 2023 Jul 1;23(1):236. doi: 10.1186/s12890-023-02534-0.
9
APACHE scoring as an indicator of mortality rate in ICU patients: a cohort study.急性生理学及慢性健康状况评分系统（APACHE）作为重症监护病房（ICU）患者死亡率的指标：一项队列研究。
Ann Med Surg (Lond). 2023 Mar 24;85(3):416-421. doi: 10.1097/MS9.0000000000000264. eCollection 2023 Mar.
10
Prevalence, imaging patterns and risk factors of interstitial lung disease in connective tissue disease: a systematic review and meta-analysis.结缔组织病相关性间质性肺疾病的流行情况、影像学表现及危险因素：系统评价和荟萃分析。
Eur Respir Rev. 2023 Mar 8;32(167). doi: 10.1183/16000617.0210-2022. Print 2023 Mar 31.

机械通气在间质性肺疾病中的应用。

The use of mechanical ventilation in interstitial lung disease.

作者信息

Nolan Timothy J, Dwyer Isabel, Geoghegan Pierce

机构信息

Royal College of Surgeons in Ireland Faculty of Medicine and Health Sciences, Anaesthesia and Critical Care, Dublin, Ireland.

Mater Misericordiae University Hospital, Faculty of Medicine, Dublin, Ireland.

出版信息

Breathe (Sheff). 2025 Apr 17;21(2):240172. doi: 10.1183/20734735.0172-2024. eCollection 2025 Apr.

DOI:10.1183/20734735.0172-2024
PMID:40255290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12004253/
Abstract

This review explores the challenges and strategies for managing mechanical ventilation in interstitial lung disease (ILD), particularly during acute exacerbations. It highlights the unique physiological barriers posed by fibrotic, non-compliant lungs, discusses evidence-based approaches to noninvasive and invasive ventilation, and emphasises the importance of balancing life-sustaining treatments with palliative care. This review aims to provide practical insights into optimising respiratory support for ILD patients while aligning treatment goals with patient prognosis and preferences.

摘要

本综述探讨了间质性肺疾病（ILD）机械通气管理中的挑战与策略，尤其是在急性加重期。它强调了纤维化、顺应性差的肺部所带来的独特生理障碍，讨论了无创和有创通气的循证方法，并强调了在维持生命的治疗与姑息治疗之间取得平衡的重要性。本综述旨在为优化ILD患者的呼吸支持提供实用见解，同时使治疗目标与患者预后和偏好相一致。