Nolan Timothy J, Dwyer Isabel, Geoghegan Pierce
Royal College of Surgeons in Ireland Faculty of Medicine and Health Sciences, Anaesthesia and Critical Care, Dublin, Ireland.
Mater Misericordiae University Hospital, Faculty of Medicine, Dublin, Ireland.
Breathe (Sheff). 2025 Apr 17;21(2):240172. doi: 10.1183/20734735.0172-2024. eCollection 2025 Apr.
This review explores the challenges and strategies for managing mechanical ventilation in interstitial lung disease (ILD), particularly during acute exacerbations. It highlights the unique physiological barriers posed by fibrotic, non-compliant lungs, discusses evidence-based approaches to noninvasive and invasive ventilation, and emphasises the importance of balancing life-sustaining treatments with palliative care. This review aims to provide practical insights into optimising respiratory support for ILD patients while aligning treatment goals with patient prognosis and preferences.
本综述探讨了间质性肺疾病(ILD)机械通气管理中的挑战与策略,尤其是在急性加重期。它强调了纤维化、顺应性差的肺部所带来的独特生理障碍,讨论了无创和有创通气的循证方法,并强调了在维持生命的治疗与姑息治疗之间取得平衡的重要性。本综述旨在为优化ILD患者的呼吸支持提供实用见解,同时使治疗目标与患者预后和偏好相一致。