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三级护理医院收治患者的心肌病模式。

Patterns of Cardiomyopathy in Patients Presenting to a Tertiary Care Hospital.

作者信息

Ullah Ikram, Khan Sher W, Fayyaz Ayesha, Khan Kamran, Ahmad Farooq, Shah Sayeeda M

机构信息

Cardiology, Northwest General Hospital and Research Centre, Peshawar, PAK.

Adult Cardiology, Lady Reading Hospital and Medical Teaching Institute, Peshawar, PAK.

出版信息

Cureus. 2025 Mar 18;17(3):e80794. doi: 10.7759/cureus.80794. eCollection 2025 Mar.

DOI:10.7759/cureus.80794
PMID:40255771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12006477/
Abstract

BACKGROUND

Cardiomyopathy is a broad category of myocardial conditions that have a substantial effect on heart function. Improving patient treatment requires a knowledge of its epidemiology.

OBJECTIVE

The aim of this study was to determine the pattern of cardiomyopathy in patients presenting to a tertiary care hospital in Peshawar, Pakistan.

METHODOLOGY

This cross-sectional study was conducted at the Department of Cardiology, Northwest General Hospital & Research Centre, Peshawar, from December 14, 2022, to June 14, 2023. There were 79 individuals with cardiomyopathy who were 16 years of age or older. Clinical and demographic information, such as age, gender, BMI, length of illness, and family history, were gathered. Cardiomyopathy patterns were classified using echocardiographic evaluations, and IBM SPSS Statistics for Windows, version 25 (IBM Corp., Armonk, NY) was employed for statistical analysis.

RESULTS

The average age of the 79 participants was 45.72 ± 2.45 years, and 40.5% (n=32) were between the ages of 51 and 60. There were 63.3% male individuals (n=50) and 36.7% female individuals (n=29). With 69.6% (n=55) and 30.4% (n=24) having a duration of symptoms ≤1 month and >1 month, respectively. 38.0% (n=30) had a family history of cardiomyopathy. With dilated, hypertrophic, and peripartum cardiomyopathy each at 15.2%, the most prevalent forms of cardiomyopathy were restrictive (20.3%, n=16), ischemic (17.7%, n=14), and arrhythmogenic right ventricular (16.5%, n=13). BMI (p = 0.000) and illness duration (p = 0.000) were substantially correlated with dilated and hypertrophic cardiomyopathies. Older age groups, especially those between the ages of 51 and 60, had a greater prevalence of cardiomyopathy (p = 0.000). Dilated cardiomyopathy (p = 0.000) and peripartum cardiomyopathy (p = 0.000) were significantly influenced by family history.

CONCLUSION

The research highlights the variety of cardiomyopathy patterns seen in a tertiary care facility, with ischemic and restrictive forms being the most prevalent. This highlights the need for specialized diagnosis and treatment strategies.

摘要

背景

心肌病是一大类对心脏功能有重大影响的心肌疾病。改善患者治疗需要了解其流行病学情况。

目的

本研究旨在确定巴基斯坦白沙瓦一家三级护理医院中就诊的心肌病患者的发病模式。

方法

这项横断面研究于2022年12月14日至2023年6月14日在白沙瓦西北综合医院及研究中心的心脏病科进行。共有79名16岁及以上的心肌病患者。收集了年龄、性别、体重指数、病程和家族史等临床和人口统计学信息。使用超声心动图评估对心肌病模式进行分类,并采用IBM SPSS Statistics for Windows 25版(IBM公司,纽约州阿蒙克)进行统计分析。

结果

79名参与者的平均年龄为45.72±2.45岁,40.5%(n=32)年龄在51至60岁之间。男性个体占63.3%(n=50),女性个体占36.7%(n=29)。症状持续时间≤1个月和>1个月的分别占69.6%(n=55)和30.4%(n=24)。38.0%(n=30)有心肌病家族史。限制性心肌病最为常见,占20.3%(n=16),其次是缺血性心肌病(17.7%,n=14)和致心律失常性右室心肌病(16.5%,n=13),扩张型、肥厚型和围产期心肌病各占15.2%。体重指数(p = 0.000)和病程(p = 0.000)与扩张型和肥厚型心肌病显著相关。年龄较大的人群,尤其是51至60岁之间的人群,心肌病患病率更高(p = 0.000)。家族史对扩张型心肌病(p = 0.000)和围产期心肌病(p = 0.000)有显著影响。

结论

该研究突出了三级护理机构中所见的心肌病模式的多样性,其中缺血性和限制性类型最为常见。这凸显了需要专门的诊断和治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c93/12006477/9df1be19cdd1/cureus-0017-00000080794-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c93/12006477/9df1be19cdd1/cureus-0017-00000080794-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c93/12006477/9df1be19cdd1/cureus-0017-00000080794-i01.jpg

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本文引用的文献

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Biomolecules. 2024 Apr 8;14(4):455. doi: 10.3390/biom14040455.
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Restrictive cardiomyopathy: definition and diagnosis.限制型心肌病:定义与诊断。
Eur Heart J. 2022 Dec 1;43(45):4679-4693. doi: 10.1093/eurheartj/ehac543.
4
Gender Related Differences in the Clinical Presentation of Hypertrophic Cardiomyopathy-An Analysis from the SILICOFCM Database.性别相关差异在肥厚型心肌病临床表型中的作用:来自 SILICOFCM 数据库的分析。
Medicina (Kaunas). 2022 Feb 18;58(2):314. doi: 10.3390/medicina58020314.
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Diagnosis and Evaluation of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review.肥厚型心肌病的诊断与评估:美国心脏病学会心血管造影与介入学会最新临床综述
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