Sakashita Katsuya, Takayama Yuichi, Takahashi Takamasa, Aoyama Hiroki, Hosoi Takahiro, Sakuma Masayoshi, Maeda Atsuyuki
Department of Surgery, Ogaki Municipal Hospital, Ogaki, Japan.
Nagoya J Med Sci. 2025 Feb;87(1):84-92. doi: 10.18999/nagjms.87.1.84.
Although conservative treatment and laparoscopic surgery are becoming increasingly popular for acute appendicitis, emergency open appendectomy is still performed in many situations. The purpose of this study was to examine the surgical outcomes of emergency open appendectomy for acute appendicitis. Between July 2008 and August 2022, 2,268 patients who underwent emergency open appendectomy for acute appendicitis were enrolled in this study. Of these patients, 417 (18.4%) had complicated appendicitis (CA), and 1,851 (81.6%) had uncomplicated appendicitis (UA). Clinical characteristics and both surgical and postoperative outcomes were compared between the groups. The percentage of CA patients increased after 2020, and by age, the proportion was greater for those aged 50 and older. In the CA group, patients were older (55.5 vs 30.0 years, p<0.001) and had more comorbidities (34% vs 12%, p<0.001). Additionally, in the CA group, the operation time was longer (86 vs 55 min, p<0.001), and the rate of postoperative complications was greater (16% vs 3.0%, p<0.001). There was one mortality in the CA group due to postoperative cerebral infarction. The postoperative hospital stay was significantly longer in the CA group (9 vs 5 days, p<0.001). In conclusion, in the CA group, the patients were older and had more comorbidities. Patients who underwent emergency open appendectomy for CA had longer operation times and more complications. This large single-center study provides insights into emergency open appendectomy for acute appendicitis and useful information in terms of comparisons with other treatment modalities, such as laparoscopic appendectomy and elective appendectomy.
尽管保守治疗和腹腔镜手术在急性阑尾炎治疗中越来越普遍,但在许多情况下仍需进行急诊开腹阑尾切除术。本研究旨在探讨急性阑尾炎急诊开腹阑尾切除术的手术效果。2008年7月至2022年8月期间,本研究纳入了2268例行急性阑尾炎急诊开腹阑尾切除术的患者。其中,417例(18.4%)为复杂性阑尾炎(CA),1851例(81.6%)为非复杂性阑尾炎(UA)。比较两组患者的临床特征、手术及术后结果。2020年后CA患者的比例增加,按年龄划分,50岁及以上患者的比例更高。CA组患者年龄更大(55.5岁 vs 30.0岁,p<0.001),合并症更多(34% vs 12%,p<0.001)。此外,CA组的手术时间更长(86分钟 vs 55分钟,p<0.001),术后并发症发生率更高(16% vs 3.0%,p<0.001)。CA组有1例患者因术后脑梗死死亡。CA组的术后住院时间明显更长(9天 vs 5天,p<0.001)。总之,CA组患者年龄更大,合并症更多。行CA急诊开腹阑尾切除术的患者手术时间更长,并发症更多。这项大型单中心研究为急性阑尾炎急诊开腹阑尾切除术提供了见解,并在与其他治疗方式(如腹腔镜阑尾切除术和择期阑尾切除术)的比较方面提供了有用信息。