Sakamoto Yusuke, Osanai Hiroyuki, Tanaka Yuki
Department of Cardiology, Tosei General Hospital, Seto, Japan.
Nagoya J Med Sci. 2025 Feb;87(1):37-50. doi: 10.18999/nagjms.87.1.37.
Catheter ablation is the first-line treatment for atrial fibrillation. Although the efficacy and safety of this procedure have been reported in older patients, they might diminish with age. Therefore, this study aimed to determine the safety and effectiveness of atrial fibrillation ablation in patients aged ≥80 years. We retrospectively analyzed the features of the catheter ablation and the subsequent clinical course and outcomes of 100 patients with atrial fibrillation aged ≥80 years who underwent ablation between July 2019 and December 2021 at Tosei General Hospital, Seto, Aichi, Japan. The average duration of atrial fibrillation was 6.0 ± 9.5 months, and 83% of the patients were symptomatic. Approximately 30% of patients developed heart failure, with 15% requiring hospitalization within one year before ablation. After ablation, 93% of patients were atrial fibrillation-free, and none required postoperative hospitalization due to heart failure. However, several complications have been observed, including cardiac tamponade, hematoma at the access site, and postoperative bradycardia. Notably, an enlarged left atrial diameter before ablation is a predictor of complications. In patients aged ≥80 years, atrial fibrillation ablation therapy demonstrated a high non-recurrence rate and may alter the progression of heart failure. Although the incidence of complications was relatively low, caution should be exercised when older patients with enlarged left atrial diameters undergo atrial fibrillation ablation.
导管消融是心房颤动的一线治疗方法。尽管该手术的疗效和安全性已在老年患者中得到报道,但随着年龄增长,其效果可能会降低。因此,本研究旨在确定年龄≥80岁患者进行心房颤动消融的安全性和有效性。我们回顾性分析了2019年7月至2021年12月期间在日本爱知县濑户市东海综合医院接受消融治疗的100例年龄≥80岁心房颤动患者的导管消融特征、随后的临床病程及结局。心房颤动的平均持续时间为6.0±9.5个月,83%的患者有症状。约30%的患者出现心力衰竭,其中15%在消融前一年内需要住院治疗。消融后,93%的患者无房颤,且无患者因心力衰竭需要术后住院治疗。然而,观察到了一些并发症,包括心脏压塞、穿刺部位血肿和术后心动过缓。值得注意的是,消融前左心房直径增大是并发症的一个预测因素。在年龄≥80岁的患者中,心房颤动消融治疗显示出较高的无复发率,并且可能改变心力衰竭的进展。尽管并发症发生率相对较低,但对于左心房直径增大的老年患者进行心房颤动消融时仍应谨慎。