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确保临床就绪:封闭孔径直线加速器兼容表面引导放射治疗系统的调试、验收和性能测试

Ensuring Clinical Readiness: Commissioning, Acceptance and Performance Testing of Closed Bore Linear Accelerator Compatible Surface Guided Radiotherapy System.

作者信息

Jadhav Anand, Gupte Ajinkya, Dandekar Prasad Raj, Rasal Sachin, Awate Omkar, Dhoundiyal Mayank

机构信息

Department of Radiation Oncology, Sir H. N. Reliance Foundation and Research Centre, Mumbai, Maharashtra, India.

出版信息

J Med Phys. 2025 Jan-Mar;50(1):148-154. doi: 10.4103/jmp.jmp_118_24. Epub 2025 Mar 24.

DOI:10.4103/jmp.jmp_118_24
PMID:40256185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12005668/
Abstract

INTRODUCTION

Surface Guided Radiation Therapy (SGRT) enhances radiation therapy by providing real-time support without additional X-ray exposure. It ensures precise patient positioning, continuous monitoring, and motion management. However, closed-bore LINACs face optical line-of-sight challenges with ceiling-mounted SGRT systems.

OBJECTIVE

This study commissions the AlignRT InBore™ SGRT system on the Ethos™ LINAC at a Mumbai tertiary care center, evaluating accuracy, precision, reproducibility, and temporal stability.

METHODS

  1. Acceptance tests per Vision RT's Form 412: Camera calibration, setup validation, thermal stability, relative shift accuracy. Phantom measurements for performance assessment. 3) Deliberate rotational motion errors to test detection capability.

RESULTS

  1. Consistent with SGRT performance on Halcyon™ LINAC (Nguyen et al.). 2) Reliable mechanical and imaging test results. 1) 51 adaptive treatment sessions. 2) High gamma pass rates confirmed clinical efficacy. 3) Essential for Ethos™ LINAC, which lacks 6D couch correction.

CONCLUSION

This study demonstrates successful SGRT integration with Ethos™, improving treatment accuracy, patient comfort, and efficiency in closed-bore LINACs, advancing radiation oncology in India.

摘要

引言

表面引导放射治疗(SGRT)通过在无额外X射线照射的情况下提供实时支持来增强放射治疗。它可确保精确的患者定位、持续监测和运动管理。然而,封闭式直线加速器在配备天花板安装的SGRT系统时面临光学视线挑战。

目的

本研究在孟买一家三级护理中心的Ethos™直线加速器上启用了AlignRT InBore™ SGRT系统,评估其准确性、精密度、可重复性和时间稳定性。

方法

1)按照Vision RT的表格412进行验收测试:相机校准、设置验证、热稳定性、相对位移准确性。使用体模测量进行性能评估。3)故意引入旋转运动误差以测试检测能力。

结果

1)与在Halcyon™直线加速器上的SGRT性能一致(Nguyen等人)。2)机械和成像测试结果可靠。1)51次自适应治疗疗程。2)高伽马通过率证实了临床疗效。3)对于缺乏六维治疗床校正功能的Ethos™直线加速器至关重要。

结论

本研究证明了SGRT与Ethos™的成功整合,提高了封闭式直线加速器的治疗准确性、患者舒适度和效率,推动了印度放射肿瘤学的发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b4/12005668/31e75d94d391/JMP-50-148-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b4/12005668/f3726ec91b55/JMP-50-148-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b4/12005668/65aee5c98616/JMP-50-148-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b4/12005668/a5e9ca66e4c3/JMP-50-148-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b4/12005668/31e75d94d391/JMP-50-148-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b4/12005668/f3726ec91b55/JMP-50-148-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b4/12005668/65aee5c98616/JMP-50-148-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b4/12005668/a5e9ca66e4c3/JMP-50-148-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b4/12005668/31e75d94d391/JMP-50-148-g004.jpg

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本文引用的文献

1
Commissioning and performance testing of the first prototype of AlignRT InBore™ a Halcyon™ and Ethos™-dedicated surface guided radiation therapy platform.AlignRT InBore™ 第一原型机的调试和性能测试,这是一款专用于 Halcyon™ 和 Ethos™ 的表面引导放射治疗平台。
Phys Med. 2020 Dec;80:159-166. doi: 10.1016/j.ejmp.2020.10.024. Epub 2020 Nov 11.
2
The Role of Optical Surface Imaging Systems in Radiation Therapy.光学表面成像系统在放射治疗中的作用。
Semin Radiat Oncol. 2018 Jun;28(3):185-193. doi: 10.1016/j.semradonc.2018.02.003.
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Minimal mask immobilization with optical surface guidance for head and neck radiotherapy.
用于头颈部放疗的基于光学表面引导的最小面罩固定技术。
J Appl Clin Med Phys. 2018 Jan;19(1):17-24. doi: 10.1002/acm2.12211. Epub 2017 Nov 9.
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Can surface imaging improve the patient setup for proton postmastectomy chest wall irradiation?表面成像能否改善质子乳房切除术后胸壁照射的患者摆位?
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