Lu Yunan, Zhang Ting, Chen Kai, Canavese Federico, Huang Chenyang, Yang Hongtao, Shi Jiahui, He Wubing, Zheng Yufeng, Chen Shunyou
Department of Pediatric Orthopedics, Fuzhou Second General Hospital, The Third Clinical Medicine College of Fujian Medical University, 47th Shangteng Road of Cangshan District, Fuzhou, 350007, Fujian, China.
Department of Emergency Trauma Surgery, Shengli Clinical Medical College of Fujian Medical University, Shengli Hospital affiliated to Fuzhou University, Fuzhou, 350001, China.
Bioact Mater. 2025 Apr 10;50:189-214. doi: 10.1016/j.bioactmat.2025.04.001. eCollection 2025 Aug.
Over the past two decades, advances in pediatric orthopedics and closed reduction combined with percutaneous internal fixation techniques have led to significant growth in pediatric orthopedics surgery. Implants such as Kirschner-wires, cannulated screws and elastic stabilization intramedullary nails are commonly used in these procedures. However, traditional implants made of metal or inert materials are not absorbable, leading to complications that affect treatment outcomes. To address this issue, absorbable materials with excellent mechanical properties, good biocompatibility, and controlled degradation rates have been developed and applied in clinical practice. These materials include absorbable polymers and biodegradable metals. This article provides a comprehensive summary of these resorbable materials from a clinician's perspective. In addition, an in-depth discussion of the feasibility of their clinical applications and related research in pediatric orthopedics is included. We found that the applications of absorbable implants in pediatric orthopedics are shifting from absorbable polymers to biodegradable metals and emphasize that the functional characteristics of resorbable materials must be coordinated and complementary to the treatment in pediatric orthopedics.
在过去二十年中,小儿骨科的进展以及闭合复位结合经皮内固定技术推动了小儿骨科手术的显著发展。克氏针、空心螺钉和弹性稳定髓内钉等植入物常用于这些手术。然而,由金属或惰性材料制成的传统植入物不可吸收,会导致影响治疗效果的并发症。为解决这一问题,已开发出具有优异机械性能、良好生物相容性和可控降解速率的可吸收材料并应用于临床实践。这些材料包括可吸收聚合物和可生物降解金属。本文从临床医生的角度对这些可吸收材料进行了全面总结。此外,还深入讨论了它们在小儿骨科临床应用的可行性及相关研究。我们发现,可吸收植入物在小儿骨科中的应用正从可吸收聚合物转向可生物降解金属,并强调可吸收材料的功能特性必须与小儿骨科治疗相协调和互补。