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小儿前臂骨折中钛质与可吸收髓内钉固定的比较

Comparison of Titanium versus Resorbable Intramedullary Nailing in Pediatric Forearm Fractures.

作者信息

Dávid Ádám László, Mucsina Flóra, Antal Eszter, Lamberti Anna Gabriella, Lőrincz Aba, Józsa Gergő

机构信息

Division of Surgery, Traumatology, Urology and Otorhinolaryngology, Department of Pediatrics, Clinical Complex, University of Pécs, 7 József Attila Street, H7623 Pécs, Hungary.

Department of Thermophysiology, Institute for Translational Medicine, Medical School, University of Pécs, 12 Szigeti Street, H7624 Pécs, Hungary.

出版信息

Children (Basel). 2024 Aug 5;11(8):942. doi: 10.3390/children11080942.

Abstract

Pediatric forearm fractures, particularly involving the shaft or diaphysis, are common injuries typically resulting from accidental trauma during various activities. Traditional treatment involves closed reduction and casting; however, surgical intervention may be necessary in certain cases. The gold standard surgical approach utilizes elastic stable intramedullary nailing (ESIN), but a newer technique uses bioabsorbable intramedullary nails made of poly(lactic-co-glycolic acid) (PLGA). This study aims to compare the outcomes of these two surgical methods in pediatric diaphyseal forearm fractures. We retrospectively reviewed 86 patients who underwent operative treatment due to the diaphyseal fractures of the forearm in the Surgical Division, Department of Pediatrics, Medical School, University of Pécs, Pécs, Hungary between 2018 and September 2022. The mean age was 9.48 (ranging from 4 to 17). A total of 41 patients underwent surgery with PLGA implants (RESIN technique), while 45 patients were treated with titanium elastic nails (ESIN technique). Various factors including patient demographics, injury mechanisms, fracture characteristics, and complications were assessed. Both groups showed similar gender distribution, with a majority of fractures occurring in boys (the male-female ratio was 31:10 in the PLGA group, while in the titanium elastic nailing (TEN) group, this ratio was 29:16, with no statistical difference between the groups ( > 0.005). The average age of the patients treated with PLGA implants (8.439 years) was lower compared to those treated with titanium nails (10.422 years). A statistically significant difference was found regarding the average age of the two groups ( = 0.0085). Left-sided injuries were more prevalent in both groups (59% of the cases in the PLGA group and 69% in the TEN group, with no statistically significant difference, = 0.716), and fractures typically involved both the radius and ulna. This represents 93% of the cases in the PLGA group and 80% in the TEN group. Regarding the involvement of bones, we also did not find a statistically significant difference ( = 0.123). The mechanisms of injury predominantly involved indirect force, such as falls (30 cases in the PLGA group and 27 cases in the TEN group), and no statistically significant difference was found ( = 0.139) regarding the mechanism of the injury. Complication rates were lower in the PLGA group (7%) compared to the titanium group (20%). The treatment of pediatric diaphyseal forearm fractures using PLGA implants appears to be a viable alternative to traditional titanium implants. Advantages include no need for secondary surgery and associated cost savings and reduced complication rate and stress associated with anesthesia and surgery. Prospective randomized trials are warranted to further validate these findings and explore long-term outcomes.

摘要

小儿前臂骨折,尤其是累及骨干或骨干的骨折,是常见的损伤,通常由各种活动中的意外创伤导致。传统治疗方法包括闭合复位和石膏固定;然而,在某些情况下可能需要手术干预。金标准手术方法是使用弹性稳定髓内钉(ESIN),但一种较新的技术使用由聚(乳酸 - 乙醇酸)(PLGA)制成的生物可吸收髓内钉。本研究旨在比较这两种手术方法治疗小儿前臂骨干骨折的效果。我们回顾性分析了2018年至2022年9月期间在匈牙利佩奇医科大学儿科学系外科因前臂骨干骨折接受手术治疗的86例患者。平均年龄为9.48岁(范围为4至17岁)。共有41例患者接受了PLGA植入物手术(RESIN技术),而45例患者接受了钛弹性钉治疗(ESIN技术)。评估了包括患者人口统计学、损伤机制、骨折特征和并发症等各种因素。两组的性别分布相似,大多数骨折发生在男孩中(PLGA组男女比例为31:10,而钛弹性钉(TEN)组该比例为29:16,两组之间无统计学差异(>0.005)。接受PLGA植入物治疗的患者平均年龄(8.439岁)低于接受钛钉治疗的患者(10.422岁)。两组患者的平均年龄存在统计学显著差异(=0.0085)。两组左侧损伤均更为常见(PLGA组59%的病例,TEN组69%的病例,无统计学显著差异,=0.716),骨折通常累及桡骨和尺骨。这在PLGA组中占93%的病例,在TEN组中占80%的病例。关于骨骼受累情况,我们也未发现统计学显著差异(=0.123)。损伤机制主要涉及间接力,如跌倒(PLGA组30例,TEN组27例),损伤机制方面未发现统计学显著差异(=0.139)。PLGA组的并发症发生率(7%)低于钛钉组(20%)。使用PLGA植入物治疗小儿前臂骨干骨折似乎是传统钛植入物的一种可行替代方案。优点包括无需二次手术、节省相关成本、降低并发症发生率以及减少与麻醉和手术相关的压力。有必要进行前瞻性随机试验以进一步验证这些发现并探索长期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d864/11352574/6ed3ec3be5e7/children-11-00942-g001.jpg

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