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比较使用激光激活的草药冲洗液在清除牙髓病原体方面的疗效:一项分析。

Comparing the efficacy of herbal irrigants using laser activation in removing endodontic pathogens: An analysis.

作者信息

Alexander Arvind Kumar, Paulaian Benin, Tamilarasan Shunmuga Priya, Nagaraj N J, Beautlin J S, Kumar Rs Mohan

机构信息

Department of Conservative Dentistry and Endodontics, Rajas Dental College and Hospital, Tirunelveli, Tamil Nadu, India.

Priyadarshini Dental College and Hospital, Thiruvallur, Tamil Nadu, India.

出版信息

J Conserv Dent Endod. 2025 Mar;28(3):237-241. doi: 10.4103/JCDE.JCDE_714_24. Epub 2025 Mar 3.

Abstract

CONTEXT

The removal of harmful endodontic pathogens involves the mechanical enlargement of the root canal space along with the use of irrigants to improve debridement and disinfection. Although this is effective in most of the cases, failures still do occur due to the microorganisms which remain inside the root canal system.

AIM

This research aims to assess the antibacterial efficacy of and , comparing them with 3% sodium hypochlorite (NaOCl), while also examining the impact of laser activation on these irrigants.

METHODOLOGY

Sixty-four single-rooted teeth with single canal were selected and decoronated to a standard length of 16 mm. All the samples were cleaned of debris and autoclaved. Two samples were selected randomly to check the complete disinfection, and the rest were inoculated with and . Biofilm formation was checked in two randomly selected samples after 7 days. The remaining samples were then divided into three groups, namely A, B, and C. Then, each group was subdivided into two subgroups (A1, A2, B1, B2, C1, and C2). Group A was irrigated with 3% NaOCl solution. Group B was irrigated with extract, and Group C was irrigated with extract. The subgroups A2, B2, and C2 were activated with Biolase diode laser, and colony-forming units (CFUs) were counted for all samples.

STATISTICAL ANALYSIS

Statistical analysis was done using analysis of variance and paired -test.

RESULTS

The mean and standard deviation of CFUs in all the groups before and after laser activation denote no significant difference.

CONCLUSION

The antibacterial activity of and was comparable with 3% NaOCl. Hence, they can be used as an alternative to the most commonly used chemical root canal irrigants. Laser activation can be used as an adjuvant in eradication of microbes from the root canal system.

摘要

背景

清除有害的牙髓病原体需要对根管空间进行机械扩大,并使用冲洗液以改善清创和消毒效果。尽管这在大多数情况下是有效的,但由于根管系统内仍残留微生物,治疗失败的情况仍会发生。

目的

本研究旨在评估[具体物质1]和[具体物质2]的抗菌效果,并将它们与3%次氯酸钠(NaOCl)进行比较,同时研究激光激活对这些冲洗液的影响。

方法

选取64颗单根管的单根牙,截冠至标准长度16 mm。所有样本均清除碎屑并进行高压灭菌。随机选取两个样本检查是否完全消毒,其余样本接种[具体物质1]和[具体物质2]。7天后,随机选取两个样本检查生物膜形成情况。然后将剩余样本分为三组,即A组、B组和C组。每组再细分为两个亚组(A1、A2、B1、B2、C1和C2)。A组用3% NaOCl溶液冲洗。B组用[提取物1]冲洗,C组用[提取物2]冲洗。亚组A2、B2和C2用Biolase二极管激光激活,对所有样本进行菌落形成单位(CFU)计数。

统计分析

采用方差分析和配对t检验进行统计分析。

结果

激光激活前后所有组CFU的平均值和标准差均无显著差异。

结论

[具体物质1]和[具体物质2]的抗菌活性与3% NaOCl相当。因此,它们可作为最常用的化学根管冲洗液的替代品。激光激活可作为从根管系统中根除微生物的辅助手段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de87/12007740/a1bffed38684/JCDE-28-237-g001.jpg

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