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全髋关节置换术(THA)后关节纤维化的手术翻修是否与良好的临床结果相关?一项对42例病例的回顾性单中心数据分析。

Is operative revision associated with favourable clinical outcomes in arthrofibrosis following total hip arthroplasty (THA)? A retrospective, single-centre data analysis of forty two cases.

作者信息

Lausmann Christian, Memarnia Navid, Salber Jochen, Sandiford Amir, Citak Mustafa, Gehrke Thorsten, Linke Philip

机构信息

Helios Endo-Klinik Hamburg, Hamburg, Germany.

Ruhr-University Bochum, Bochum, Germany.

出版信息

Int Orthop. 2025 Apr 21. doi: 10.1007/s00264-025-06533-0.

DOI:10.1007/s00264-025-06533-0
PMID:40257586
Abstract

PURPOSE

There is a paucity of clinical studies examining outcomes following surgical revision in cases of histologically confirmed arthrofibrosis after total hip arthroplasty (THA). Consequently, the aim of this study is to present the clinical outcomes and to identify risk factors for poor clinical and functional outcome following surgical intervention for histologically confirmed arthrofibrosis following THA.

METHODS

This study included 51 patients (51 hips) with histologically confirmed arthrofibrosis of the hip based on the synovial-like interface membrane (SLIM) criteria. These were selected from 7983 revision THA cases performed during the study period After exclusion criteria were applied, 42 cases (59.5% women) with an average age of 63.6 years were included. The mean duration of follow up was 70 months (range 30-122 months). Of these, 73.8% underwent index surgery after primary THA implantation. The primary indication for revision surgery was predominantly the clinical suspicion of arthrofibrosis (n = 35). The Harris Hip Score (HHS) and the EQ-5D-3 L scores were calculated for all cases at the time of follow-up. For the risk analysis of a poor clinical outcome, two groups were divided according to the Harris Hip Score. The group with a poor clinical outcome was defined as a HHS < 55.

RESULTS

Open arthrolysis was performed in all cases with a modular component being replaced in 73.8% of cases (n = 31) and only two cases requiring additional revision of the femoral and acetabular components due to aseptic loosening.The mean pre op Harris Hip Score (HHS) was 53.2 before revision surgery. This increased to 65.7 post op (p < 0.001). Only 34.1% of patients achieved the minimum clinical significance difference (MCID) of 18 HHS points after surgical revision. The EQ-5D Visual Analogue Scale (VAS) score and the Time Trade-Off (TTO) score averaged 0.226 (SD 0.245) and 0.221 (SD 0.37). Complications occurred in seven cases (16.7%,), with dislocation in 2 cases and persistent AF symptoms in 3 cases. Six cases required further revision surgery (14.3%). In three cases, a further open arthrolysis was performed due to persistent symptoms. Increased BMI (30.1 vs. 26.7 BMI, p < 0.05) or higher body weight (88.4 kg vs. 78.7 kg, p = 0.086), smoking and a lower preoperative HHS (p = 0.022) were identified as risk factors for a poor clinical outcome, defined as HHS < 55.

CONCLUSION

Results of this study suggest that mid-term clinical results following surgical intervention for arthrofibrosis following THA show a moderate to poor postoperative outcome with an acceptable complication rate. Risk factors for a poor outcome such as increased weight, BMI or smoking should be considered and critically assessed preoperatively.

摘要

目的

目前关于全髋关节置换术(THA)后经组织学证实的关节纤维化病例手术翻修后结局的临床研究较少。因此,本研究的目的是呈现临床结局,并确定THA后经组织学证实的关节纤维化手术干预后临床和功能结局不佳的风险因素。

方法

本研究纳入了51例(51髋)根据滑膜样界面膜(SLIM)标准经组织学证实为髋关节纤维化的患者。这些患者选自研究期间进行的7983例THA翻修病例。应用排除标准后,纳入42例患者(59.5%为女性),平均年龄63.6岁。平均随访时间为70个月(范围30 - 122个月)。其中,73.8%的患者在初次THA植入后接受了翻修手术。翻修手术的主要指征主要是临床怀疑关节纤维化(n = 35)。在随访时计算所有病例的Harris髋关节评分(HHS)和EQ - 5D - 3L评分。为了分析临床结局不佳的风险,根据Harris髋关节评分将患者分为两组。临床结局不佳的组定义为HHS < 55。

结果

所有病例均进行了开放性关节松解术,73.8%的病例(n = 31)更换了模块化组件,仅有2例因无菌性松动需要额外翻修股骨和髋臼组件。翻修手术前的平均Harris髋关节评分(HHS)为53.2。术后增至65.7(p < 0.001)。手术翻修后只有34.1%的患者达到了18分HHS的最小临床重要差异(MCID)。EQ - 5D视觉模拟量表(VAS)评分和时间权衡(TTO)评分分别平均为0.226(标准差0.245)和0.221(标准差0.37)。7例(16.7%)发生并发症,2例脱位,3例持续存在关节纤维化症状。6例需要进一步翻修手术(14.3%)。3例因症状持续进行了再次开放性关节松解术。较高的BMI(30.1 vs. 26.7 BMI,p < 0.05)或更高的体重(88.4 kg vs. 78.7 kg,p = 0.086)、吸烟以及较低的术前HHS(p = 0.022)被确定为临床结局不佳(定义为HHS < 55)的风险因素。

结论

本研究结果表明THA后关节纤维化手术干预后的中期临床结果显示术后结局中度至较差,但并发症发生率可接受。术前应考虑并严格评估体重增加、BMI或吸烟等不良结局的风险因素。

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