Davies Ella P, Tsuboi Motoyuki, Evans Jayne, Rowley Jane, Korenromp Eline L, Clayton Tim, Chico R Matthew
Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Int J STD AIDS. 2025 Jul;36(8):611-621. doi: 10.1177/09564624251333489. Epub 2025 Apr 21.
IntroductionWe conducted a global systematic review and meta-analysis of gonorrhoea and chlamydia among men who have sex with men (MSM) from 2000 to 2022.MethodsWe searched four databases to identify studies conducted between 1 January 2000 and 19 April 2022 that reported prevalence from aetiological assays. We extracted data, calculated point estimates, corrected and then pooled them using random-effects models. We stratified results by United Nations regions and conducted subgroup analyses established Results172 studies met our inclusion criteria, providing 387 prevalence data points from 57 countries. The overall pooled prevalence for gonorrhoea was 7.2% [95% CI: 6.0 to 8.5; 188 data points; = 347,253] and for chlamydia was 9.9% (95% CI: 8.8 to 11.0; 190 data points; = 342,799). For gonorrhoea, pooled prevalence between 2000 and 2010 was 5.0% (95% CI: 3.7 to 6.5; 89 data points; = 78,557) compared to 9.3% (7.7-11.1; 99 data points; = 268,696) between 2011 and 2022, < 0.001. For chlamydia, pooled prevalence between 2000 to 2010 was 6.6% (95% CI: 5.4 to 7.9; 95 data points; = 91,015) compared to 13.6% (12.0-15.2; 95 data points; = 251,784) between 2011 and 2022, < 0.001.ConclusionA holistic approach is needed to reduce the curable STIs burden among MSM.
引言
我们对2000年至2022年期间男男性行为者（MSM）中的淋病和衣原体感染进行了一项全球系统评价和荟萃分析。
方法
我们检索了四个数据库，以确定2000年1月1日至2022年4月19日期间进行的、报告了病因学检测患病率的研究。我们提取数据，计算点估计值，进行校正，然后使用随机效应模型进行汇总。我们按联合国区域对结果进行分层，并进行亚组分析。
结果
172项研究符合我们的纳入标准，提供了来自57个国家的387个患病率数据点。淋病的总体汇总患病率为7.2%[95%置信区间：6.0至8.5；188个数据点；n = 347,253]，衣原体感染的总体汇总患病率为9.9%（95%置信区间：8.8至11.0；190个数据点；n = 342,799）。对于淋病，2000年至2010年期间的汇总患病率为5.0%（95%置信区间：3.7至6.5；89个数据点；n = 78,557），而2011年至2022年期间为9.3%（7.7 - 11.1；99个数据点；n = 268,696），P < 0.001。对于衣原体感染，2000年至2010年期间的汇总患病率为6.6%（95%置信区间：5.4至7.9；95个数据点；n = 91,015），而2011年至2022年期间为13.6%（12.0 - 15.2；95个数据点；n = 251,784），P < 0.001。
结论
需要采取整体方法来减轻男男性行为者中可治愈性传播感染的负担。
