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Less is more? Antidepressant effects of short-acting psychedelics.

作者信息

Ramaekers Johannes G

机构信息

Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.

出版信息

Neuropsychopharmacology. 2025 May;50(6):875-876. doi: 10.1038/s41386-025-02103-5. Epub 2025 Apr 22.

DOI:10.1038/s41386-025-02103-5
PMID:40258989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12032289/
Abstract
摘要

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本文引用的文献

1
Rapid and sustained antidepressant effects of vaporized N,N-dimethyltryptamine: a phase 2a clinical trial in treatment-resistant depression.汽化N,N-二甲基色胺的快速且持续的抗抑郁作用：一项针对难治性抑郁症的2a期临床试验
Neuropsychopharmacology. 2025 May;50(6):895-903. doi: 10.1038/s41386-025-02091-6. Epub 2025 Apr 22.
2
Benefits and Challenges of Ultra-Fast, Short-Acting Psychedelics in the Treatment of Depression.超快速、短效迷幻剂治疗抑郁症的益处与挑战
Am J Psychiatry. 2025 Jan 1;182(1):33-46. doi: 10.1176/appi.ajp.20230890.
3
A phase 1/2 trial to assess safety and efficacy of a vaporized 5-methoxy-N,N-dimethyltryptamine formulation (GH001) in patients with treatment-resistant depression.一项1/2期试验，旨在评估一种汽化5-甲氧基-N,N-二甲基色胺制剂（GH001）对难治性抑郁症患者的安全性和疗效。
Front Psychiatry. 2023 Jun 20;14:1133414. doi: 10.3389/fpsyt.2023.1133414. eCollection 2023.
4
Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression.单次剂量裸盖菇素治疗难治性重度抑郁症发作。
N Engl J Med. 2022 Nov 3;387(18):1637-1648. doi: 10.1056/NEJMoa2206443.
5
Parsing the Hippocampus in Depression: Chronic Stress, Hippocampal Volume, and Major Depressive Disorder.剖析抑郁症中的海马体：慢性应激、海马体体积与重度抑郁症
Biol Psychiatry. 2019 Mar 15;85(6):436-438. doi: 10.1016/j.biopsych.2019.01.011.