Sato Jin, Hino Hideki, Watanabe Ryota, Mori Takashi
Department of Anesthesiology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
JA Clin Rep. 2025 Apr 21;11(1):23. doi: 10.1186/s40981-025-00785-w.
Ozaki surgery, which reconstructs cardiac valves using autologous pericardium, is commonly performed for aortic valve replacement and offers benefits such as avoiding anticoagulation and reducing valve degeneration. However, its application to pulmonary valve replacement remains rare, and anesthetic management for such cases is not well documented.
A 71-year-old woman with severe aortic and pulmonary valve stenosis underwent double valve replacement using the Ozaki procedure and coronary artery bypass grafting. Post-cardiopulmonary bypass, she developed severe pulmonary hypertension and systemic hypotension. Norepinephrine exacerbated pulmonary hypertension, while arginine vasopressin effectively stabilized systemic pressure without worsening pulmonary pressure.
This is the first reported case of anesthetic management for double valve replacement using the Ozaki procedure. Adequate use of vasopressin led to ameliorating pulmonary hypertension after cardiopulmonary bypass. Assessing preoperative right ventricular pressure and selecting appropriate vasopressors are crucial in mitigating perioperative pulmonary hypertension.
尾崎手术使用自体心包重建心脏瓣膜,常用于主动脉瓣置换,具有避免抗凝和减少瓣膜退变等优点。然而,其在肺动脉瓣置换中的应用仍然很少,此类病例的麻醉管理也缺乏充分记录。
一名71岁女性,患有严重的主动脉瓣和肺动脉瓣狭窄,接受了使用尾崎手术的双瓣膜置换术和冠状动脉搭桥术。体外循环后,她出现了严重的肺动脉高压和全身性低血压。去甲肾上腺素加重了肺动脉高压,而精氨酸加压素有效稳定了全身血压,且未使肺动脉压力恶化。
这是首例关于使用尾崎手术进行双瓣膜置换术的麻醉管理报告病例。充分使用加压素可改善体外循环后的肺动脉高压。术前评估右心室压力并选择合适的血管加压药对于减轻围手术期肺动脉高压至关重要。