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自体心包重建二叶式主动脉瓣——三尖瓣化的效用

Reconstruction of bicuspid aortic valve with autologous pericardium--usefulness of tricuspidization.

作者信息

Ozaki Shigeyuki, Kawase Isamu, Yamashita Hiromasa, Uchida Shin, Nozawa Yukinari, Takatoh Mikio, Hagiwara So, Kiyohara Nagaki

机构信息

Department of Cardiovascular Surgery, Toho University Ohashi Medical Center.

出版信息

Circ J. 2014;78(5):1144-51. doi: 10.1253/circj.cj-13-1335. Epub 2014 Mar 7.

Abstract

BACKGROUND

This study describes the surgical treatment of bicuspid aortic valve with original aortic valve reconstruction.

METHODS AND RESULTS

Aortic valve reconstruction was done in 102 patients with bicuspid aortic valve from April 2007 through September 2011. Thirty-four patients with ascending aortic diameter >45 mm underwent hemi-arch aortic replacement concomitantly. Seventy-seven patients had aortic stenosis, and 25 had aortic regurgitation (AR). Mean age was 63.7±10.0 years old. There were 55 men and 47 women. Harvested pericardium is treated with 0.6% glutaraldehyde solution. The distance between commissures is measured with an original sizing instrument. For bicuspid valve with raphe, the raphe is considered as a commissure in order to measure the distance between each commissure. Without a raphe, we create a new annular margin and commissure using coronary ostium and the sizing instrument as a guide. Then, pericardium is trimmed with original template. Three cusps are sutured independently. The preoperative averaged peak pressure gradient of 71.1±39.0 mmHg was decreased to 16.2±8.8, 13.3±6.0, and 13.9±5.6 mmHg, respectively 1 week, 1 year, and 3 years after operation. AR was trivial. One reoperation was recorded. Mean follow-up was 733 days. There were 5 late mortalities. No thromboembolic event was recorded.

CONCLUSIONS

Medium-term results were excellent. Tricuspidization gave good opening and closure of aortic valve with excellent hemodynamics.

摘要

背景

本研究描述了采用原始主动脉瓣重建术治疗二叶式主动脉瓣的手术方法。

方法与结果

2007年4月至2011年9月,对102例二叶式主动脉瓣患者进行了主动脉瓣重建术。34例升主动脉直径>45 mm的患者同时接受了半弓主动脉置换术。77例患者有主动脉狭窄,25例有主动脉反流(AR)。平均年龄为63.7±10.0岁。男性55例,女性47例。采集的心包用0.6%的戊二醛溶液处理。用原始尺寸测量仪测量瓣叶交界之间的距离。对于有嵴的二叶式瓣膜,将嵴视为一个交界,以测量每个交界之间的距离。对于没有嵴的情况,我们以冠状动脉开口和尺寸测量仪为引导创建一个新的瓣环边缘和交界。然后,用原始模板修剪心包。独立缝合三个瓣叶。术前平均峰值压力梯度为71.1±39. mmHg,术后1周、1年和3年分别降至16.2±8.8 mmHg、13.3± 和13.9±5.6 mmHg。主动脉反流轻微。记录到1例再次手术。平均随访733天。有5例晚期死亡。未记录到血栓栓塞事件。

结论

中期结果良好。三尖瓣化使主动脉瓣开启和关闭良好,血流动力学优异。

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