Tu Xinhang, Junna Mithri R, Kolla Bhanu Prakash
Center for Sleep Medicine, Mayo Clinic, Rochester, Minnesota.
J Clin Sleep Med. 2025 Aug 1;21(8):1499-1502. doi: 10.5664/jcsm.11740.
Sleep disturbance is highly prevalent during pregnancy, and there are no guidelines clearly appraising pharmacological treatment for insomnia during pregnancy. Furthermore, the data on the efficacy and safety of nonbenzodiazepine benzodiazepine receptor agonists in pregnant patients are inconclusive. We present a case of insomnia during pregnancy that was managed with doxylamine and zolpidem and discuss the current evidence examining the efficacy and potential adverse effects of treatment with a focus on the nonbenzodiazepine benzodiazepine receptor agonists in the management of insomnia during pregnancy.
Tu X, Junna MR, Kolla BP. How do you Zzz during pregnancy? A brief review of Z-drug use and management of insomnia during pregnancy. . 2025;21(8):1499-1502.
睡眠障碍在孕期非常普遍,且尚无明确评估孕期失眠药物治疗的指南。此外,关于非苯二氮䓬类苯二氮䓬受体激动剂在孕妇中的疗效和安全性的数据尚无定论。我们报告一例孕期失眠患者使用多西拉敏和唑吡坦治疗的病例,并讨论目前关于治疗疗效和潜在不良反应的证据,重点关注非苯二氮䓬类苯二氮䓬受体激动剂在孕期失眠管理中的应用。
Tu X, Junna MR, Kolla BP. 孕期如何入睡?孕期使用Z类药物及失眠管理的简要综述。. 2025;21(8):1499 - 1502。