• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Comparative pharmacokinetics of febantel and its metabolites in sheep and cattle.

作者信息

Delatour P, Tiberghien M P, Garnier F, Benoît E

出版信息

Am J Vet Res. 1985 Jun;46(6):1399-402.

PMID:4026020
Abstract

The pharmacokinetics of febantel and its main metabolites were studied in cattle and sheep. Seven ewes and 4 heifers were given febantel orally in a single dose of 7.5 mg/kg, 25 mg/kg, or 45 mg/kg of body weight. Plasma concentrations vs time of febantel and individual metabolites were determined by high-performance liquid chromatography analysis. Intestinal absorption of febantel was faster and biotransformations were more active in sheep than in cattle.

摘要

相似文献

1
Comparative pharmacokinetics of febantel and its metabolites in sheep and cattle.
Am J Vet Res. 1985 Jun;46(6):1399-402.
2
Comparative microsomal oxidation of febantel and its metabolite fenbendazole in various animal species.非班太尔及其代谢产物芬苯达唑在不同动物物种中的微粒体氧化比较。
Xenobiotica. 1989 Jan;19(1):97-100. doi: 10.3109/00498258909034681.
3
Pharmacokinetics of fenbendazole in sheep.芬苯达唑在绵羊体内的药代动力学
Am J Vet Res. 1981 Jul;42(7):1146-8.
4
Metabolite concentrations in plasma following treatment of cattle with five anthelmintics.
Res Vet Sci. 1985 Sep;39(2):173-8.
5
A high performance liquid chromatographic method for the determination of febantel and its major metabolites in lamb plasma.
Biomed Chromatogr. 1993 Mar-Apr;7(2):78-81. doi: 10.1002/bmc.1130070206.
6
In vitro febantel transformation by sheep and cattle ruminal fluids and metabolism by hepatic subcellular fractions from different animal species.通过绵羊和牛瘤胃液进行非班太尔的体外转化以及不同动物物种肝脏亚细胞组分的代谢
Biochem Pharmacol. 1987 Oct 1;36(19):3107-14. doi: 10.1016/0006-2952(87)90619-8.
7
The bioavailability of febantel in dehydrated camels.非班太尔在脱水骆驼中的生物利用度。
J Vet Pharmacol Ther. 1996 Aug;19(4):288-94. doi: 10.1111/j.1365-2885.1996.tb00051.x.
8
Disposition of fenbendazole in cattle.
Am J Vet Res. 1987 Jun;48(6):958-61.
9
A re-assessment of the efficacy of febantel (Rintal) and fenbendazole (Panacur) against Strongyloides papillosus in sheep and goats.对非班太尔(Rintal)和芬苯达唑(Panacur)治疗绵羊和山羊乳头类圆线虫效果的重新评估。
J S Afr Vet Assoc. 1980 Mar;51(1):49-50.
10
[Metabolism-embryotoxicity relationship of febantel in the rat and the sheep].
Ann Rech Vet. 1982;13(2):163-70.

引用本文的文献

1
[Esophageal closure and the efficacy of febantel against Muellerius capillaris in goats].[山羊食管闭锁及非班太尔对毛细缪勒线虫的疗效]
Can Vet J. 1995 Nov;36(11):714-6.
2
The pharmacokinetics of fenbendazole and oxfendazole in cattle.
Vet Res Commun. 1984 Aug;8(3):187-93. doi: 10.1007/BF02214711.