Nozari Ali, Haji Abbas Oghli Farnaz, Parvizi Fatemeh, Jowkar Zahra, Pakniyat Jahromi Maryam, Hamidi Seyed Ahmadreza
Department of Pediatric Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Oral and Dental Disease Research Center, Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Clin Exp Dent Res. 2025 Apr;11(2):e70131. doi: 10.1002/cre2.70131.
This study aimed to assess the impact of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and proanthocyanidin (PA) on the microshear bond strength (μSBS) of universal adhesives to caries-affected dentin (CAD) in primary teeth.
160 human primary second molars with occlusal caries were utilized, with CAD-exposed dentin surfaces. The teeth were categorized into four groups based on CAD pretreatment: no pretreatment, CPP-ACP for 3 min, PA for 1 min, and PA for 1 min followed by CPP-ACP for 3 min. Each group subdivided into four based on adhesive system (Gluma Bond Universal or All-Bond Universal) and application mode (etch and rinse; E&R or self-etch; SE). Following composite resin restoration, μSBS measurements were taken after 24 h of water storage.
PA pretreatment showed the highest μSBS compared to controls and other methods (p < 0.001). Conversely, CAD pretreatment with CPP-ACP + PA led to lower μSBS than the control (p = 0.009). Universal adhesive choice significantly influenced μSBS (p < 0.001), with Gluma Bond Universal outperforming All-Bond Universal (p < 0.001). The E&R method demonstrated superior bond strength over SE (p < 0.001).
CAD pretreatment, particularly with PA, significantly impacted bond strength, with Gluma Bond Universal and the E&R method proving optimal for enhancing μSBS to CAD. These findings offer valuable insights for refining adhesive protocols in pediatric dentistry, potentially improving clinical outcomes in restorative procedures.
本研究旨在评估酪蛋白磷酸肽 - 无定形磷酸钙（CPP - ACP）和原花青素（PA）对通用粘合剂与乳牙龋损牙本质（CAD）的微剪切粘结强度（μSBS）的影响。
使用160颗患有咬合面龋的人类原发性第二磨牙，其牙本质表面暴露有CAD。根据CAD预处理方法将牙齿分为四组：未预处理、CPP - ACP处理3分钟、PA处理1分钟、PA处理1分钟后再用CPP - ACP处理3分钟。根据粘合剂系统（Gluma Bond Universal或All - Bond Universal）和应用方式（酸蚀冲洗；E&R或自酸蚀；SE），每组再细分为四组。复合树脂修复后，在水储存24小时后进行μSBS测量。
与对照组和其他方法相比，PA预处理显示出最高的μSBS（p < 0.001）。相反，用CPP - ACP + PA对CAD进行预处理导致μSBS低于对照组（p = 0.009）。通用粘合剂的选择对μSBS有显著影响（p < 0.001），Gluma Bond Universal的性能优于All - Bond Universal（p < 0.001）。E&R方法显示出比SE更高的粘结强度（p < 0.001）。
CAD预处理，特别是PA预处理，对粘结强度有显著影响，Gluma Bond Universal和E&R方法被证明是提高与CAD的μSBS的最佳方法。这些发现为改进儿童牙科的粘结方案提供了有价值的见解，可能改善修复程序的临床结果。
