Boschat J, Guiserix J, Etienne Y, Gilard M, Blanc J J, Penther P
Ann Cardiol Angeiol (Paris). 1985 Jun;34(6):393-9.
Complete proximal occlusion of the the anterior interventricular artery was associated with the presence (group A: 31 cases) or the absence (group B: 31 cases) of transmural myocardial necrosis in the corresponding territory. The aim of this study was to define the factors which determine the development of permanent myocardial necrosis, on the basis of clinical, electrocardiographic, haemodynamic and angiographic criteria. Group B was characterised by the following features: almost all of the patients (30 out of 31) had unstable angina, for less than 2 months in half of the cases; 67% of cases presented an abnormality of ventricular repolarisation on the resting ECG, usually (54 per cent of cases) in leads V3 to V5, suggestive of isolated sub-pericardial ischaemia in half of these cases; 24 cases presented moderate regional hypokinesia in the anteroapical territory of the LV; the distal AIV artery was more clearly visualised (17 cases had a well perfused AIV artery compared with 6 in group A) and a greater number of patients obtained homocoronary interseptal re-perfusion (8 versus 2) and heterocoronary re-perfusion by distal anastomosis of the AIV artery and the PIV artery by the apex (13 versus 3) (p less than 0.05) than in group A. However, the possibility of surgery was considered to be limited (39%) on the basis of the angiographic criteria. Thus, in group B, a "phantom AIV artery syndrome" can not be distinguished from unstable angina on the basis of the clinical and electrocardiographic profile.(ABSTRACT TRUNCATED AT 250 WORDS)
前室间动脉完全近端闭塞与相应区域透壁心肌坏死的存在(A组:31例)或不存在(B组:31例)相关。本研究的目的是根据临床、心电图、血流动力学和血管造影标准确定决定永久性心肌坏死发生的因素。B组具有以下特征:几乎所有患者(31例中的30例)患有不稳定型心绞痛,半数病例病程不到2个月;67%的病例静息心电图出现心室复极异常,通常(54%的病例)出现在V3至V5导联,其中半数病例提示孤立性心外膜下缺血;24例患者左心室心尖前区出现中度节段性运动减弱;远端前室间动脉更清晰可见(A组6例,B组17例前室间动脉灌注良好),通过前室间动脉与后室间动脉在心尖处远端吻合获得同冠状动脉间隔再灌注(A组2例,B组8例)和异冠状动脉再灌注的患者数量更多(A组3例,B组13例)(p<0.05)。然而,根据血管造影标准,手术可能性被认为有限(39%)。因此,在B组中,根据临床和心电图表现无法将“假性前室间动脉综合征”与不稳定型心绞痛区分开来。(摘要截短至250字)