Steg A, Conquy S, Teyssier P, Amar E, Schrameck E, Boiteux J P
Ann Urol (Paris). 1985;19(4):283-7.
The role of carcinogenic factors following urinary diversion are here studied on the basis of three very different cases. In the first, an adenocarcinoma developed at the site of a ureterocolic anastomosis thirty one years after Coffey's operation for bladder exstrophy. In the second, the tumor had developed, 31 years after uretero-sigmoidostomy, for ureteral trauma. The anastomosis had moreover ceased to function ten years previously. In the third case, the patient had undergone a right nephrectomy for urinary tuberculosis and a colocystoplasty to enlarge the bladder with re-implantation of the left ureter in the graft. Twenty one years later, an adenocarcinoma developed at the site of the anastomosis between the colonic graft and the bladder. This was an exceptional case (possibly the first) of a cryptal tumor developing out of contact with material. It thus runs counter to the alleged role of facies in the development of adenocarcinomas following urinary diversion.
本文基于三个截然不同的病例,研究了尿路改道后致癌因素的作用。第一个病例中,在因膀胱外翻接受科菲手术31年后,输尿管结肠吻合口处发生了腺癌。第二个病例中,输尿管乙状结肠造口术后31年,因输尿管创伤发生了肿瘤。此外,该吻合口在十年前就已不再发挥功能。在第三个病例中,患者因肾结核接受了右肾切除术,并进行了结肠膀胱扩大术,将左输尿管重新植入移植物中。21年后,在结肠移植物与膀胱的吻合口处发生了腺癌。这是一例罕见的(可能是首例)与物质接触无关的隐窝肿瘤病例。因此,这与所谓的尿路改道后腺癌发生中颜面的作用相悖。