所选抗菌剂对迟缓爱德华氏菌的体外比较活性
Comparative in vitro activities of selected antimicrobial agents against Edwardsiella tarda.
作者信息
Reinhardt J F, Fowlston S, Jones J, George W L
出版信息
Antimicrob Agents Chemother. 1985 Jun;27(6):966-7. doi: 10.1128/AAC.27.6.966.
Abstract
MICs of 14 antimicrobial agents for 29 strains of Edwardsiella tarda were determined by an agar dilution method. Of the agents tested, ciprofloxacin, enoxacin, and norfloxacin were the most active on a weight basis. All strains were also susceptible to clinically achievable concentrations of ampicillin, chloramphenicol, tetracycline, trimethoprim, sulfamethoxazole, trimethoprim plus sulfamethoxazole, cefotaxime, and gentamicin. Ninety percent of the strains demonstrated high-level resistance to polymyxin B and colistin.
摘要
采用琼脂稀释法测定了14种抗菌药物对29株迟缓爱德华氏菌的最低抑菌浓度（MIC）。在所测试的药物中，环丙沙星、依诺沙星和诺氟沙星按重量计算活性最强。所有菌株对临床可达到浓度的氨苄西林、氯霉素、四环素、甲氧苄啶、磺胺甲恶唑、甲氧苄啶加磺胺甲恶唑、头孢噻肟和庆大霉素也敏感。90%的菌株对多粘菌素B和黏菌素表现出高水平耐药。
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