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针刺治疗单纯性肥胖的“神经-内分泌-免疫”调节机制研究进展

[Research progress on the "neuro-endocrine-immune" regulatory mechanism of acupuncture in the treatment of simple obesity].

作者信息

Xie Wen-Ting, Ye Yu-Juan, Ma Cui, Wei Yu-Ting, Yan Xing-Ke

机构信息

School of Acupuncture-Moxibustion and Massage, Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China.

出版信息

Zhen Ci Yan Jiu. 2025 Apr 25;50(4):459-466. doi: 10.13702/j.1000-0607.20231051.

Abstract

Acupuncture has a definite effect on the treatment of simple obesity. Acupuncture can effectively reduce the weight of patients and improve the body metabolism. Studies have shown that acupuncture in the treatment of simple obesity is closely related to the regulation of neuro-endocrine-immune function. This article reviews the neuro-endocrine-immune regulatory mechanism of acupuncture in the treatment of simple obesity from the aspects of regulating key nuclei of the central nervous system, improving insulin and leptin resistance, regulating glucose and lipid metabolism, intestinal flora disorders, and regulating related immune inflammatory molecules and inflammatory signaling pathways. This review aims to provide a basis for the mechanism and application research of acupuncture in the treatment of simple obesity.

摘要

针灸对单纯性肥胖的治疗有确切疗效。针灸能有效减轻患者体重,改善机体代谢。研究表明,针灸治疗单纯性肥胖与神经 - 内分泌 - 免疫功能的调节密切相关。本文从调节中枢神经系统关键核团、改善胰岛素和瘦素抵抗、调节糖脂代谢、肠道菌群紊乱以及调节相关免疫炎症分子和炎症信号通路等方面综述了针灸治疗单纯性肥胖的神经 - 内分泌 - 免疫调节机制。本综述旨在为针灸治疗单纯性肥胖的机制及应用研究提供依据。

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