Watanabe T, Fujita H, Koizumi A, Chiba K, Miyasaka M, Ikeda M
Arch Environ Health. 1985 May-Jun;40(3):170-6. doi: 10.1080/00039896.1985.10545912.
Lead concentrations were determined for more than 2500 blood samples (more than 2000 winter samples and approximately 500 summer samples) collected from farmers in various parts of Japan to establish reliable baselines for blood lead levels; the analysis was conducted in a single laboratory to avoid any inter-laboratory errors. Blood lead levels distributed log-normally with a geometric mean (i.e., a geometric standard deviation) of 48.6 micrograms/L (1.51) for males and 32.1 micrograms/L (1.50) for females. The levels observed were among the lowest in the industrialized countries of the world. The sex difference was significant (P less than .01) while the difference in Pb-B between winter and summer was essentially insignificant. Both drinking and smoking habits were associated with a dose-dependent increase in blood lead levels, especially in males; the increment was additive when the examinee was a drinker-smoker. The geographical difference in blood lead levels remained inconclusive.
对从日本各地农民采集的2500多个血样（2000多个冬季血样和约500个夏季血样）进行铅浓度测定，以建立可靠的血铅水平基线；分析在单个实验室进行，以避免任何实验室间误差。血铅水平呈对数正态分布，男性几何均值（即几何标准差）为48.6微克/升（1.51），女性为32.1微克/升（1.50）。观察到的血铅水平在世界工业化国家中处于最低水平。性别差异显著（P小于0.01），而冬季和夏季之间的血铅差异基本不显著。饮酒和吸烟习惯均与血铅水平呈剂量依赖性增加有关，尤其是在男性中；当受检者既饮酒又吸烟时，这种增加是累加的。血铅水平的地理差异尚无定论。
